P. Goldman-Rakic

Publications340
h-index148
Citations70,031
Highly Influential Citations2,797
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Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex.
1. An oculomotor delayed-response task was used to examine the spatial memory functions of neurons in primate prefrontal cortex. Monkeys were trained to fixate a central spot during a brief… Expand
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Cellular basis of working memory
In the presence of normal sensory and motor capacity, intelligent behavior is widely acknowledged to develop from the interaction of short-and long-term memory. While the behavioral, cellular, and… Expand
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Synaptic mechanisms and network dynamics underlying spatial working memory in a cortical network model.
Single-neuron recordings from behaving primates have established a link between working memory processes and information-specific neuronal persistent activity in the prefrontal cortex. Using a… Expand
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Modulation of memory fields by dopamine Dl receptors in prefrontal cortex
Dopamine has been implicated in the cognitive process of working memory but the cellular basis of its action has yet to be revealed. By combining iontophoretic analysis of dopamine receptors with… Expand
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Dual streams of auditory afferents target multiple domains in the primate prefrontal cortex
'What' and 'where' visual streams define ventrolateral object and dorsolateral spatial processing domains in the prefrontal cortex of nonhuman primates. We looked for similar streams for… Expand
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Longitudinal topography and interdigitation of corticostriatal projections in the rhesus monkey
Anterograde tracing methods were used to examine the topographic organization and interrelationship of projections to the neostriatum arising from various areas of association cortex. In contrast to… Expand
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Heterogeneity in the pyramidal network of the medial prefrontal cortex
The prefrontal cortex is specially adapted to generate persistent activity that outlasts stimuli and is resistant to distractors, presumed to be the basis of working memory. The pyramidal network… Expand
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Posterior parietal cortex in rhesus monkey: II. Evidence for segregated corticocortical networks linking sensory and limbic areas with the frontal lobe
We have examined the circuitry connecting the posterior parietal cortex with the frontal lobe of rhesus monkeys. HRP‐WGA and tritiated amino acids were injected into subdivisions 7m, 7a, 7b, and 7ip… Expand
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Dissociation of object and spatial processing domains in primate prefrontal cortex.
Areas and pathways subserving object and spatial vision are segregated in the visual system. Experiments show that the primate prefrontal cortex is similarly segregated into object and spatial… Expand
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The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive.
  • P. Goldman-Rakic
  • Psychology, Medicine
  • Philosophical transactions of the Royal Society…
  • 29 October 1996
The functional architecture of prefrontal cortex is central to our understanding of human mentation and cognitive prowess. This region of the brain is often treated as an undifferentiated structure,… Expand
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