RCAN1 gene

Known as: Regulator of Calcineurin 1 Gene, DOWN SYNDROME CRITICAL REGION GENE 1, CALCIPRESSIN 1 
This gene is involved in modulation of protein phosphorylation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
0102019952018

Papers overview

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2011
2011
Individuals with Down syndrome (DS) will inevitably develop Alzheimer disease (AD) neuropathology sometime after middle age… (More)
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2007
2007
Oxidative stress (OS) underlies neuronal dysfunction in many neurodegenerative disorders. Regulator of Calcineurin 1 (RCAN1 or… (More)
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Highly Cited
2006
Highly Cited
2006
Trisomy 21 results in Down's syndrome, but little is known about how a 1.5-fold increase in gene dosage produces the pleiotropic… (More)
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Highly Cited
2006
Highly Cited
2006
Hyperphosphorylated tau proteins accumulate in the paired helical filaments of neurofibrillary tangles seen in such tauopathies… (More)
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Highly Cited
2004
Highly Cited
2004
We conducted a genome-wide analysis of genes that are regulated by vascular endothelial growth factor (VEGF) in endothelial cells… (More)
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Highly Cited
2003
Highly Cited
2003
The calcium/calmodulin-dependent protein phosphatase calcineurin stimulates cardiac hypertrophy in response to numerous stimuli… (More)
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Highly Cited
2000
Highly Cited
2000
The protein phosphatase calcineurin mediates many cellular responses to calcium signals. Using a genetic screen in yeast, we… (More)
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Highly Cited
2000
Highly Cited
2000
Down syndrome is one of the major causes of mental retardation and congenital heart malformations. Other common clinical features… (More)
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Highly Cited
1997
Highly Cited
1997
Down syndrome is a major cause of mental retardation and congenital heart defects and is due to the presence of three copies of… (More)
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Highly Cited
1995
Highly Cited
1995
Down syndrome is a major cause of mental retardation and congenital heart defects. While most of the affected individuals have… (More)
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