K. Davies

Publications344
h-index103
Citations39,893
Highly Influential Citations1,112
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Mitochondrial free radical generation, oxidative stress, and aging.
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Free radicals and tissue damage produced by exercise.
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Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations.
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Oxidative stress: the paradox of aerobic life.
  • K. Davies
  • Biology
    Biochemical Society symposium
  • 1 November 1995
TLDR
The paradox of aerobic life, or the 'Oxygen Paradox', is that higher eukaryotic aerobic organisms cannot exist without oxygen, yet oxygen is inherently dangerous to their existence and oxidative damage remains an inescapable outcome of aerobic existence.
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Oxidative Stress, Antioxidant Defenses, and Damage Removal, Repair, and Replacement Systems
TLDR
A remarkable array of systems for defense; damage removal, replacement, and repair; adaptation; growth modulation; and apoptosis make it possible for us to enjoy life in an oxygen‐rich environment.
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The oxidative inactivation of mitochondrial electron transport chain components and ATPase.
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Degradation of oxidized proteins by the 20S proteasome.
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HSP70 and other possible heat shock or oxidative stress proteins are induced in skeletal muscle, heart, and liver during exercise.
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Free radical biology and medicine: it's a gas, man!
TLDR
Gasses that can affect oxidative stress and that themselves may be radicals are reviewed, fearing that many of the gasses discussed in this review will induce transient adaptive responses in gene expression that enable cells and tissues to survive.
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Regulatory mechanisms controlling expression of the DAN/TIR mannoprotein genes during anaerobic remodeling of the cell wall in Saccharomyces cerevisiae.
The DAN/TIR genes of Saccharomyces cerevisiae encode homologous mannoproteins, some of which are essential for anaerobic growth. Expression of these genes is induced during anaerobiosis and in some…
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