RCAN1 wt Allele

Known as: ADAPT78, RCN1, Regulator of Calcineurin 1 wt Allele 
Human RCAN1 wild-type allele is located in the vicinity of 21q22.12 and is approximately 99 kb in length. This allele, which encodes calcipressin-1… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Down’s syndrome (DS) is a genetic disorder caused by full or partial trisomy of human chromosome 21 and presents with many… (More)
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Highly Cited
2009
Highly Cited
2009
The incidence of many cancer types is significantly reduced in individuals with Down’s syndrome, and it is thought that this… (More)
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Highly Cited
2008
Highly Cited
2008
Individuals with Down syndrome (DS) and Ts65Dn mice (a major animal model of DS) carry an extra copy of the DSCR1 (Down Syndrome… (More)
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Highly Cited
2004
Highly Cited
2004
We conducted a genome-wide analysis of genes that are regulated by vascular endothelial growth factor (VEGF) in endothelial cells… (More)
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Highly Cited
2001
Highly Cited
2001
The DSCR1 (Adapt78) gene was independently discovered as a resident of the "Down syndrome candidate region"and as an "adaptive… (More)
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Highly Cited
2000
Highly Cited
2000
Down syndrome is one of the major causes of mental retardation and congenital heart malformations. Other common clinical features… (More)
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Highly Cited
2000
Highly Cited
2000
Calcineurin, a calcium/calmodulin-regulated protein phosphatase, modulates gene expression in cardiac and skeletal muscles during… (More)
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Highly Cited
2000
Highly Cited
2000
McCDPK1 is a salinity- and drought-induced calcium-dependent protein kinase (CDPK) isolated from the common ice plant… (More)
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Highly Cited
1997
Highly Cited
1997
Down syndrome is a major cause of mental retardation and congenital heart defects and is due to the presence of three copies of… (More)
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Highly Cited
1995
Highly Cited
1995
Down syndrome is a major cause of mental retardation and congenital heart defects. While most of the affected individuals have… (More)
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