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Down Syndrome

Known as: Downs Syndrome, Down's syndrome, Trisomy 21 Syndrome 
A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
The psychological well-being of mothers raising a child with a developmental disability varies with the nature of the disability… Expand
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Review
2000
Review
2000
29. Cited by Tsuchiya, Kenzaburo: The relation of occupation to cancer, especially cancer of the lung. Cancer, 1965, 18, 136-144… Expand
Review
2000
Review
2000
Evidence is reviewed for a developmentally-emerging behavioral phenotype in individuals with Down syndrome that includes… Expand
Highly Cited
1999
Highly Cited
1999
The aims of this longitudinal study were: (1) to assess the continuity and change in diagnosis, intelligence, and language skills… Expand
Highly Cited
1995
Highly Cited
1995
Trisomy 21 or Down syndrome (DS) is the most frequent genetic cause of mental retardation, affecting one in 800 live born human… Expand
Highly Cited
1995
Highly Cited
1995
DOWN'S syndrome (DS) or trisomy 21 is the most common genetic cause of mental retardation1. Development of the DS brain is… Expand
Highly Cited
1994
Highly Cited
1994
Down syndrome (DS) is a major cause of mental retardation and congenital heart disease. Besides a characteristic set of facial… Expand
Highly Cited
1989
Highly Cited
1989
Interleukin 1, an immune response-generated cytokine that stimulates astrocyte proliferation and reactivity (astrogliosis), was… Expand
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Highly Cited
1985
Highly Cited
1985
We have purified and characterized the cerebral amyloid protein that forms the plaque core in Alzheimer disease and in aged… Expand
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Highly Cited
1985
Highly Cited
1985
One hundred brains of patients with Down's syndrome(DS) who died in insstitutions for chronic care were exemined for… Expand