Acute Megakaryocytic Leukemias

Known as: LEUKEMIA, MEGAKARYOCYTIC, MALIGNANT, Thrombocytic leukemia, Acute Megakaryoblastic Leukemia 
An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone… (More)

Topic mentions per year

Topic mentions per year

1946-2017
0204019462016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Ets-related gene (ERG) is a member of the ETS transcription factor gene family located on Hsa21. ERG is known to have a crucial… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Tyrosine kinases are aberrantly activated in numerous malignancies, including acute myeloid leukemia (AML). To identify tyrosine… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Individuals with Down syndrome (DS) are predisposed to develop acute megakaryoblastic leukemia (AMKL), characterized by… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2005
Highly Cited
2005
An activating 1849G>T mutation of JAK2 (Janus kinase 2) tyrosine kinase was recently described in chronic myeloproliferative… (More)
  • figure 1
  • table 1
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The phosphatidylinositol 3-kinase (PI3K)/AKT protein kinase pathway is involved in cell growth, proliferation, and apoptosis. The… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Children with constitutional trisomy 21 (Down syndrome) have an approximately 500-fold increased risk of developing acute… (More)
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Children with Down syndrome have a 10–20-fold elevated risk of developing leukemia, particularly acute megakaryoblastic leukemia… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
t(1;22) is the principal translocation of acute megakaryoblastic leukemias. Here we show this chromosomal rearrangement to result… (More)
  • figure 1
  • figure 2
Is this relevant?
2000
2000
Acute megakaryocytic leukemia (AMegL) is a rare subtype of acute myeloid leukemia (AML) evolving from primitive megakaryoblasts… (More)
Is this relevant?
Highly Cited
1985
Highly Cited
1985
A megakaryoblastic cell line, designated MEG-01, was established from the bone marrow of a patient with blast crisis of… (More)
  • figure 1
  • figure 3
  • table 1
  • table 3
  • table 2
Is this relevant?