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Amyloid beta-Peptides

Known as: beta-Peptide, Amyloid, beta-Protein, Alzheimer, Amyloid AD-AP 
Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found… Expand
National Institutes of Health

Papers overview

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Review
2002
Review
2002
It has been more than 10 years since it was first proposed that the neurodegeneration in Alzheimer's disease (AD) may be caused… Expand
Highly Cited
2002
Highly Cited
2002
Although extensive data support a central pathogenic role for amyloid β protein (Aβ) in Alzheimer's disease, the amyloid… Expand
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Review
2001
Review
2001
  • D. Selkoe
  • Physiological reviews
  • 2001
  • Corpus ID: 12949249
Rapid progress in deciphering the biological mechanism of Alzheimer's disease (AD) has arisen from the application of molecular… Expand
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Highly Cited
1999
Highly Cited
1999
Cerebral deposition of amyloid beta peptide (Abeta) is an early and critical feature of Alzheimer's disease. Abeta generation… Expand
Highly Cited
1994
Highly Cited
1994
Normal processing of the amyloid beta protein precursor (beta APP) results in secretion of a soluble 4-kilodalton protein… Expand
Highly Cited
1993
Highly Cited
1993
Several variants of the beta amyloid protein, differing only at their carboxy terminus (beta 1-39, beta 1-40, beta 1-42, and beta… Expand
Highly Cited
1993
Highly Cited
1993
Amyloid beta-peptide (A beta) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer… Expand
Highly Cited
1993
Highly Cited
1993
Apolipoprotein E (apoE), a plasma apolipoprotein that plays a central role in lipoprotein metabolism, is localized in the senile… Expand
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Highly Cited
1992
Highly Cited
1992
In Alzheimer's disease (AD), abnormal accumulations of beta-amyloid are present in the brain and degenerating neurons exhibit… Expand
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Highly Cited
1990
Highly Cited
1990
The amyloid beta peptide (A beta P) is a small fragment of the much larger, broadly distributed amyloid precursor protein (APP… Expand