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Amyloid beta-Peptides
Known as:
beta-Peptide, Amyloid
, beta-Protein, Alzheimer
, Amyloid AD-AP
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Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found…
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National Institutes of Health
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Related topics
Related topics
30 relations
Narrower (16)
AAKLVFF
AN-1792
amyloid beta-peptide (17-43)
amyloid beta-protein (1-12)
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APP protein, human
Alzheimer's Disease
Cerebral Amyloid Angiopathy
Down Syndrome
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
The role of insulin receptor signaling in the brain
L. Plum
,
M. Schubert
,
J. Brüning
Trends in endocrinology and metabolism
2005
Corpus ID: 15845248
Highly Cited
2003
Highly Cited
2003
Enhanced Proteolysis of β-Amyloid in APP Transgenic Mice Prevents Plaque Formation, Secondary Pathology, and Premature Death
M. Leissring
,
Wesley Farris
,
+5 authors
D. Selkoe
Neuron
2003
Corpus ID: 15414029
Review
2001
Review
2001
Clearing the Brain's Amyloid Cobwebs
D. Selkoe
Neuron
2001
Corpus ID: 17860343
Highly Cited
2000
Highly Cited
2000
Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes.
T. Miura
,
Kiyoko Suzuki
,
Naohito Kohata
,
H. Takeuchi
Biochemistry
2000
Corpus ID: 30950167
Aggregation of the amyloid beta-peptide (Abeta) into insoluble fibrils is a key pathological event in Alzheimer's disease. Zn(II…
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Highly Cited
1999
Highly Cited
1999
Conformational transitions of islet amyloid polypeptide (IAPP) in amyloid formation in vitro.
R. Kayed
,
J. Bernhagen
,
+4 authors
A. Kapurniotu
Journal of Molecular Biology
1999
Corpus ID: 46508917
Amyloid aggregates have been recognized to be a pathological hallmark of several fatal diseases, including Alzheimer's disease…
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Highly Cited
1997
Highly Cited
1997
Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.
M. Yaar
,
S. Zhai
,
+4 authors
Barbara A. Gilchrest
Journal of Clinical Investigation
1997
Corpus ID: 12951044
Alzheimer's disease is a neurodegenerative disorder characterized by the extracellular deposition in the brain of aggregated beta…
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Highly Cited
1996
Highly Cited
1996
On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.
A. Lomakin
,
D. S. Chung
,
G. Benedek
,
Daniel A. Kirschner
,
D. Teplow
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 10509626
We have studied the fibrillogenesis of synthetic amyloid beta-protein-(1-40) fragment (A beta) in 0.1 M HCl. At low pH, A beta…
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Review
1994
Review
1994
Normal and abnormal biology of the beta-amyloid precursor protein.
D. Selkoe
Annual Review of Neuroscience
1994
Corpus ID: 7265646
Few macromolecules have become the object of more intense chemical and biological scrutiny in recent years than has the l3…
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Highly Cited
1990
Highly Cited
1990
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
E. Koo
,
S. Sisodia
,
+6 authors
D. Price
Proceedings of the National Academy of Sciences…
1990
Corpus ID: 25921723
In the brains of aged humans and cases of Alzheimer disease, deposits of amyloid in senile plaques are located in proximity to…
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Highly Cited
1988
Highly Cited
1988
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
R. Tanzi
,
A. McClatchey
,
E. Lamperti
,
L. Villa-komaroff
,
J. Gusella
,
R. Neve
Nature
1988
Corpus ID: 4277294
Amyloid B-protein/amyloid A4 is a peptide present in the neuritic plaques, neurofibrillary tangles and cerebrovascular deposits…
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