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APP protein, human

Known as: AAA, ABPP, APP 
Amyloid beta A4 protein (770 aa, ~87 kDa) is encoded by the human APP gene. This protein is involved in cell surface receptor-mediated signaling and… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Background Emerging research suggests that mobile apps can be used to effectively treat common mental illnesses like depression… Expand
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Review
2018
Review
2018
This review focuses on the role of prenatal hypoxia in the development of brain functions in the postnatal period and subsequent… Expand
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Review
2018
Review
2018
Alzheimer’s disease (AD) is the most common cause of age-related dementia leading to severe irreversible cognitive decline and… Expand
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Review
2018
Review
2018
Alzheimer disease (AD) is a debilitating dementia believed to result from the deposition of extracellular amyloid-β (A… Expand
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Review
2018
Review
2018
Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by amyloid plaques in patients’ brain tissue. The… Expand
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Review
2018
Review
2018
Alzheimer´s disease (AD) is a devastating neurodegenerative disease of the elderly population. Genetic evidence strongly suggests… Expand
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Review
2017
Review
2017
Amyloid beta peptide (Aβ) is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein… Expand
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Review
2017
Review
2017
Background: Alzheimer’s disease (AD) is the most common neurodegenerative disorder, neu-ropathologically characterized by… Expand
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Highly Cited
1999
Highly Cited
1999
Proteolytic processing of the amyloid precursor protein (APP) generates amyloid β (Aβ) peptide, which is thought to be causal for… Expand
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Highly Cited
1996
Highly Cited
1996
To determine whether the presenilin 1 (PS1), presenilin 2 (PS2) and amyloid β-protein precursor (APP) mutations linked to… Expand