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APP wt Allele

Known as: AAA, ABPP, CVAP 
Human APP wild-type allele is located in the vicinity of 22q13.2 and is approximately 290 kb in length. This allele, which encodes amyloid beta A4… 
National Institutes of Health

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Related topics

16 relations
21q21.3ALZHEIMER DISEASE, FAMILIAL, 1APP geneAPP protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization.
Accurate measurement of estradiol (E2) is important in clinical diagnostics and research. High sensitivity methods are critical… 
2008
2008
Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.
Cleavage of the amyloid precursor protein (APP) by beta- and gamma-secretases results in generation of the amyloid-beta protein… 
2007
2007
Additional lymph node examination from entire submission of residual mesenteric tissue in colorectal cancer specimens may not add clinical and pathologic relevance.
Highly Cited
2004
Highly Cited
2004
Terbutaline Is a Developmental Neurotoxicant: Effects on Neuroproteins and Morphology in Cerebellum, Hippocampus, and Somatosensory Cortex
β2-Adrenoceptor agonists, especially terbutaline, are widely used to arrest preterm labor, but they also cross the placenta to… 
Highly Cited
2004
Highly Cited
2004
Atmospheric pressure photoionization-mass spectrometry with a microchip heated nebulizer.
A novel, microfabricated heated nebulizer chip for atmospheric pressure photoionization-mass spectrometry (APPI-MS) is presented… 
2004
2004
Atmospheric pressure photo-ionization liquid chromatography/mass spectrometric determination of aflatoxins in food
A comparison between electrospray ionization (ESI) and the recent introduced atmospheric pressure photo-ionization (APPI… 
Highly Cited
2003
Highly Cited
2003
Development of LC/MS/MS methods for cocktail dosed Caco-2 samples using atmospheric pressure photoionization and electrospray ionization.
Good reliability of Caco-2 permeability studies requires competent sampling and analytical methods to ensure the comparability of… 
2000
2000
CADASIL: Notch signaling defect or protein accumulation problem?
When studies of the genetic etiology of human disease intersect with those of basic mechanisms in developmental biology, our… 
1998
1998
Spatial and temporal expression of AP-1 responsive rod photoreceptor genes and bZIP transcription factors during development of the rat retina.
PURPOSE The promoter region of the rod-specific beta subunit of cGMP PDE (beta-PDE) and opsin genes contains highly conserved cis… 
1996
1996
Novel phosphonium salts display in vitro and in vivo cytotoxic activity against human ovarian cancer cell lines.
Phosphonium salts are part of a class of lipophilic cationic molecules that accumulate preferentially in mitochondria and inhibit… 
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