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Proto-Oncogenes

Known as: c-ONC, Cellular Oncogene, Cellular Oncogenes 
Oncogenes are altered forms of normal cellular genes called proto-oncogene. Many proto-oncogenes are homologous to viral oncogenes and involved in… 
National Institutes of Health

Related topics

Related topics

17 relations

Narrower (13)

BCL2 protein, humanCSF1R geneERBB2 geneFOS Family Genes
Gene Mutationaspects of radiation effectsphysiological aspects

Broader (1)

Genes

Papers overview

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Highly Cited
1993
Highly Cited
1993
Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4.
Transgenic mice carrying the Wnt-1 protooncogene modified for expression in mammary epithelial cells exhibit hyperplastic mammary… 
Highly Cited
1993
Highly Cited
1993
The oncogenic potential of deregulated homeobox genes.
Homeobox genes encode DNA-binding proteins that regulate gene expression during embryonic development. Deregulation of homeobox… 
Highly Cited
1991
Highly Cited
1991
IL-4 regulates c-kit proto-oncogene product expression in human mast and myeloid progenitor cells.
The c-kit proto-oncogene encodes the receptor for a novel hemopoietic cytokine, termed stem cell factor (SCF) or mast cell growth… 
Highly Cited
1990
Highly Cited
1990
K-ras activation in neoplasms of the human female reproductive tract.
The role of cellular oncogenes in the development of epithelial tumors of the human female reproductive tract has not previously… 
Highly Cited
1989
Highly Cited
1989
Structure and expression of the rat c-jun messenger RNA: tissue distribution and increase during chemical hepatocarcinogenesis.
c-jun is the cellular homologue of the recently isolated nuclear oncogene v-jun. This protooncogene encodes the cellular… 
Highly Cited
1985
Highly Cited
1985
Expression of p21ras in fresh primary and metastatic human colorectal tumors.
Activation of the cellular oncogene ras has been implicated in many types of human malignancies. In this study, the relative… 
Highly Cited
1985
Highly Cited
1985
Regulation of c-myc mRNA levels in normal human lymphocytes by modulators of cell proliferation.
Increased expression of the cellular oncogene c-myc has recently been demonstrated in some types of proliferating non-neoplastic… 
Review
1985
Review
1985
Transcription Control by Oncogenes
Highly Cited
1984
Highly Cited
1984
Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.
The nucleotide sequence encoding the transforming polyprotein of the McDonough strain of feline sarcoma virus was determined… 
Highly Cited
1984
Highly Cited
1984
Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation
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