Gene Mutation

Known as: Gene Mutation Type, DNA Alteration, Gene Alteration 
The result of any gain, loss or alteration of the sequences comprising a gene, including all sequences transcribed into RNA.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
UNLABELLED Molecular classifications defining new tumor subtypes have been recently refined with genetic and transcriptomic… (More)
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Highly Cited
2005
Highly Cited
2005
Most gastrointestinal stromal tumors (GIST) have an activating mutation in either KIT or PDGFRA. Imatinib is a selective tyrosine… (More)
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Highly Cited
2004
Highly Cited
2004
CONTEXT Germline mutations of the genes encoding succinate dehydrogenase subunits B (SDHB) and D (SDHD) predispose to… (More)
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Highly Cited
2001
Highly Cited
2001
Clinical studies with the Abl tyrosine kinase inhibitor STI-571 in chronic myeloid leukemia demonstrate that many patients with… (More)
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Highly Cited
1999
Highly Cited
1999
Cellular immunophenotypic studies were performed on a cohort of randomly selected IgM(+) B-chronic lymphocytic leukemia (B-CLL… (More)
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Highly Cited
1999
Highly Cited
1999
The mechanisms by which circadian pacemaker systems transmit timing information to control behavior are largely unknown. Here, we… (More)
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Highly Cited
1999
Highly Cited
1999
Internal tandem duplication of the FLT3 gene and point mutations of the N-RAS gene are the most frequent somatic mutations… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The results of retrospective and prospective case-control studies have clearly established that mild elevations of the… (More)
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Highly Cited
1990
Highly Cited
1990
BACKGROUND AND METHODS The plasma cholesteryl-ester transfer protein (CETP) catalyzes the transfer of cholesteryl esters from… (More)
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