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Frameshift Mutation function

Known as: Out-of-Frame Mutations, frame-shift mutation, Reading Frame Shift Mutation 
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby… 
National Institutes of Health

Related topics

Related topics

16 relations
CYP2C19*2 AlleleCYP2C19*3 AlleleCYP2C8*5 AlleleCYP2C9*6 Allele

Broader (2)

Gene MutationMutation

Narrower (1)

Out-of-Frame Deletion

Papers overview

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1995
1995
Microsatellite instability is an early genetic event in myelodysplastic syndrome.
To the Editor: alterations, such as karyotypic abnormalities and N-RAS and Tf53 mutations.2” are closely associated with the… 
Highly Cited
1993
Highly Cited
1993
DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.
Chemical carcinogens such as the aromatic amide 2-acetylaminofluorene (AAF) are known to induce -1 frameshift mutation hotspots… 
1988
1988
Bulge-out structures in the single-stranded trimer AUA and in the duplex (CUGGUGCGG).(CCGCCCAG). A model-building and NMR study.
Model-building studies were carried out on the trimer AUA. Bulge-out structures which allow incorporation into a continuous RNA… 
Highly Cited
1986
Highly Cited
1986
Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain.
Complementary DNA (cDNA) encoding a human T-cell gamma chain has been cloned and sequenced. At the junction of the variable and… 
1985
1985
Mutagenicity of the fractionated organic emissions from diesel, cigarette smoke condensate, coke oven, and roofing tar in the Ames assay.
Mobile and stationary combustion sources emit particle-bound organics that, after extraction, are mutagenic to Salmonella… 
1983
1983
Intracistronic complementation in the simian virus 40 A gene.
A set of eight simian virus 40 mutants was constructed with lesions in the A gene, which encodes the large tumor (T) antigen… 
1980
1980
Development of a somatic mutation screening system using Hb mutants. IV. Successful detection of red cells containing the human frameshift mutants Hb Wayne and Hb Cranston using monospecific…
The production and purification of antibodies detecting Hb Wayne, an alpha-globin frameshift mutant, and Hb Cranston, a beta… 
Highly Cited
1977
Highly Cited
1977
Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex.
9-Aminoacridine forms a crystalline complex with the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine. We have solved… 
Highly Cited
1972
Highly Cited
1972
Association of induced frameshift mutagenesis and DNA replication in Escherichia coli.
The induction of frameshifts in E. coli seems to be associated with chromosome replication. 
Highly Cited
1968
Highly Cited
1968
Spontaneous and ICR191-A-induced Frameshift Mutations in the A Gene of Escherichia coli Tryptophan Synthetase
Frameshift mutant trpA21 was isolated after ultraviolet treatment and frameshift mutant trpA540 after ICR191-A (an acridine…