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Frameshift Mutation function

Known as: Out-of-Frame Mutations, frame-shift mutation, Reading Frame Shift Mutation 
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby… 
National Institutes of Health

Related topics

Related topics

16 relations
CYP2C19*2 AlleleCYP2C19*3 AlleleCYP2C8*5 AlleleCYP2C9*6 Allele

Broader (2)

Gene MutationMutation

Narrower (1)

Out-of-Frame Deletion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Functional loss of IB leads to NF-B deregulation in aggressive chronic lymphocytic leukemia
Abbreviations used: BcR, B cell receptor; CD40L, CD40 ligand; CLL, chronic lymphocytic leukemia; DLBCL, diffuse large B cell… 
Highly Cited
2002
Highly Cited
2002
Overexpression of the tomato Asc-1 gene mediates high insensitivity to AAL toxins and fumonisin B1 in tomato hairy roots and confers resistance to Alternaria alternata f. sp. lycopersici in Nicotiana…
The sphinganine-analog mycotoxins (SAMs) fumonisin B1 and AAL toxins are inhibitors of eukaryotic sphinganine N-acyltransferase… 
Highly Cited
1997
Highly Cited
1997
Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus.
The ssgA gene of Streptomyces griseus B2682, when present in high copy number, results in both suppression of sporulation and… 
Highly Cited
1993
Highly Cited
1993
DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.
Chemical carcinogens such as the aromatic amide 2-acetylaminofluorene (AAF) are known to induce -1 frameshift mutation hotspots… 
Highly Cited
1984
Highly Cited
1984
Demonstration of the production of frameshift and base-substitution mutations by quasipalindromic DNA sequences.
The in vivo production of frameshift and base-substitution mutations predicted as a consequence of the metabolic processing of… 
Review
1979
Review
1979
Molecular genetics of human hemoglobin synthesis.
Molecular analysis of normal and abnormal human globin genes and their gene products has recently provided information on the… 
Highly Cited
1977
Highly Cited
1977
Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex.
9-Aminoacridine forms a crystalline complex with the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine. We have solved… 
Highly Cited
1977
Highly Cited
1977
Frameshift mutagenicity of certain naturally occurring phenolic compounds in the 'Salmonella/microsome' test: activation of anthraquinone and flavonol glycosides by gut bacterial enzymes [proceedings…
Janiszowska, W. & Pennock, J. F. (1976) Vitam. Horm. (N. Y.) 34, 77-107 Kratz, W. A. & Myers, J. (1955) Am. J. Bot. 42, 282-288… 
Highly Cited
1972
Highly Cited
1972
Association of induced frameshift mutagenesis and DNA replication in Escherichia coli.
The induction of frameshifts in E. coli seems to be associated with chromosome replication. 
Highly Cited
1968
Highly Cited
1968
Spontaneous and ICR191-A-induced Frameshift Mutations in the A Gene of Escherichia coli Tryptophan Synthetase
Frameshift mutant trpA21 was isolated after ultraviolet treatment and frameshift mutant trpA540 after ICR191-A (an acridine… 
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