Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Frameshift Mutation function

Known as: Out-of-Frame Mutations, frame-shift mutation, Reading Frame Shift Mutation 
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
BACKGROUND Approximately 50 to 60% of patients with essential thrombocythemia or primary myelofibrosis carry a mutation in the… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2013
Highly Cited
2013
BACKGROUND Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular… Expand
  • figure 2
  • table 1
  • table 1
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Nod2 activates the NF-κB pathway following intracellular stimulation by bacterial products. Recently, mutations inNod2 have been… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Scurfy (sf) is an X-linked recessive mouse mutant resulting in lethality in hemizygous males 16–25 days after birth, and is… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Rett syndrome (RTT, MIM 312750) is a progressive neurodevelopmental disorder and one of the most common causes of mental… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The extreme obesity of the obese (ob/ob) mouse is attributable to mutations in the gene encoding leptin, an adipocyte-specific… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 1
Is this relevant?
Highly Cited
1994
Highly Cited
1994
A putative tumor suppressor locus on the short arm of human chromosome 9 has been localized to a region of less than 40 kilobases… Expand
Is this relevant?
Highly Cited
1992
Highly Cited
1992
We have generated mice that carry a germline mutation in which a large portion of the RAG-2 coding region is deleted. Homozygous… Expand
Is this relevant?
Highly Cited
1983
Highly Cited
1983
The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al… Expand
  • table 2
  • table 4
  • figure 2
Is this relevant?