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Frameshift Mutation function

Known as: Out-of-Frame Mutations, frame-shift mutation, Reading Frame Shift Mutation 
A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby… 
National Institutes of Health

Related topics

Related topics

16 relations
CYP2C19*2 AlleleCYP2C19*3 AlleleCYP2C8*5 AlleleCYP2C9*6 Allele

Broader (2)

Gene MutationMutation

Narrower (1)

Out-of-Frame Deletion

Papers overview

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Highly Cited
1997
Highly Cited
1997
A 1-kb Alu-mediated germ-line deletion removing BRCA1 exon 17.
Although more than 100 different BRCA1 germ-line mutations have already been identified in breast and/or ovarian cancer families… 
Highly Cited
1991
Highly Cited
1991
Characterization of an alpha 1----3-galactosyltransferase homologue on human chromosome 12 that is organized as a processed pseudogene.
UDP-Gal:Gal beta 1----4GlcNAc alpha 1----3-galactosyltransferase is a terminal glycosyltransferase that is widely expressed in a… 
Highly Cited
1991
Highly Cited
1991
Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16
To examine the biological properties of the bovine papillomavirus type 1 (BPV) and human papillomavirus type 16 (HPV16) E5 genes… 
Highly Cited
1986
Highly Cited
1986
Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activity.
A series of mutations in open reading frame (ORF) E5 of bovine papillomavirus type 1 has been constructed to determine whether… 
Highly Cited
1985
Highly Cited
1985
An artificial anchor domain: hydrophobicity suffices to stop transfer
Highly Cited
1985
Highly Cited
1985
The histidine permease gene (HIP1) of Saccharomyces cerevisiae.
Highly Cited
1985
Highly Cited
1985
DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli. A correlation between the conformation of the premutagenic lesion and the mutation specificity.
Highly Cited
1984
Highly Cited
1984
Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli. Strain specificity and mutation-prone sequences.
Highly Cited
1978
Highly Cited
1978
Mutagenicity of Filtrates from Respirable Coal Fly Ash
Incubation of histidine-requiring auxotrophs of the bacterium Salmonella typhimurium with cyclohexane-, saline-, and serum… 
Highly Cited
1971
Highly Cited
1971
Hycanthone: A Frameshift Mutagen
Rapid spot-test screening of antischistosomal agents reveals that hycanthone is a potent frameshift mutagen while the closely… 
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