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CYP2C19*3 Allele

Known as: CYP2C19, W212X, CYP2C19, c.636G>A, CYP2C19, m2 
Human CYP2C19*3 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type… 
National Institutes of Health

Related topics

Related topics

12 relations
10q24.1-q24.3Frameshift Mutation functionGuanosine to Adenosine Transition AbnormalityInactive - Biochemical Activity Level

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Prevalence of the CYP2C19*2 (681 G>A), *3 (636 G>A) and *17 (−806 C>T) alleles among an Iranian population of different ethnicities
Polymorphisms in the cytochrome P (CYP) 450 family may cause adverse drug responses in individuals. Cytochrome P450 2C19 (CYP2C19… 
2018
2018
A synergic effect between CYP2C19*2, CYP2C19*3 loss-of-function and CYP2C19*17 gain-of-function alleles is associated with Clopidogrel resistance among Moroccan Acute Coronary Syndromes patients
The main objective of our study was to investigate the association of CYP2C19*2 and CYP2C19*3 loss-of-function and CYP2C19*17… 
2013
2013
Polymorphisms of MDR1, CYP2C19 and P2Y12 genes in Indian population: effects on clopidogrel response.
Review
2013
Review
2013
High prevalence of CYP2C19*2 allele in Roma samples: study on Roma and Hungarian population samples with review of the literature
The purpose of our study was to characterise the CYP2C19*2 and CYP2C19*3 alleles in healthy Roma and Hungarian populations. DNA… 
Highly Cited
2011
Highly Cited
2011
Effect of CYP2C19*2 and *3 Loss-of-Function Alleles on Platelet Reactivity and Adverse Clinical Events in East Asian Acute Myocardial Infarction Survivors Treated With Clopidogrel and Aspirin
Background— As compared with whites, East Asians more often carry the cytochrome P450 (CYP) 2C19 loss-of-function (LOF) allele… 
2011
2011
Association of CYP2C19*3 gene polymorphism with breast cancer in Chinese women.
Cytochrome P450 (CYP) 2C19 metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids, which significantly… 
Highly Cited
2010
Highly Cited
2010
Assessment of CYP2C19 genetic polymorphisms in a korean population using a simultaneous multiplex pyrosequencing method to simultaneously detect the CYP2C19*2, CYP2C19*3, and CYP2C19*17 alleles
Background and objective:  CYP2C19 is a drug‐metabolizing enzyme showing various genetic polymorphisms that may cause marked… 
2010
2010
SCREENING FOR CYP2C19*2, *3 AND *4 GENE VARIANTS IN A ROMANIAN POPULATION STUDY GROUP
CYP2C19, a member of the cytochrome P450 enzymes family, metabolizes a range of clinically significant drugs. Its homologous gene… 
2008
2008
A high incidence of polymorphic CYP2C19 variants in archival blood samples from Papua New Guinea
There is considerable inter-ethnic variability in the incidence of CYP2C19 genetic poor metabolisers (var/var). About 3 per cent… 
2002
2002
CYP2C19 genotype and S-mephenytoin 4′-hydroxylation phenotype in a Chinese Dai population
Abstract.Aims: To investigate the incidence of the CYP2C19 polymorphism in the Chinese Dai population. Methods: One hundred and… 
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