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CYP2C19*2 Allele

Known as: CYP2C19, m1A, CYP2C19, c.681G>A, CYP2C19, m1 
Human CYP2C19*2 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type… Expand
National Institutes of Health

Papers overview

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2017
2017
OBJECTIVE To investigate the contribution of CYP2C19 polymorphisms and body mass index (BMI) in the development of endometriosis… Expand
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2016
2016
Voriconazole (VCZ) use is limited by its narrow therapeutic range and significant interpatient variability in exposure. This… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Prospective assessment of pharmacogenetic strategies has been limited by an inability to undertake bedside genetic… Expand
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Highly Cited
2010
Highly Cited
2010
AIMS despite treatment with clopidogrel on top of aspirin, stent thrombosis (ST) still occurs being the most serious complication… Expand
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Highly Cited
2010
Highly Cited
2010
INTRODUCTION The prodrug, clopidogrel, plays an important role in the prevention of thrombotic events in patients undergoing… Expand
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2010
2010
BACKGROUND AND OBJECTIVE CYP2C19 is a drug-metabolizing enzyme showing various genetic polymorphisms that may cause marked… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Clopidogrel and low-dose aspirin have become the mainstay oral antiplatelet regimen to prevent recurrent ischaemic… Expand
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Highly Cited
2008
Highly Cited
2008
AimTo study the pharmacokinetic characteristics of voriconazole in healthy Chinese male volunteers in relation to cytochrome P450… Expand
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Highly Cited
1998
Highly Cited
1998
The 4'-hydroxylation of the S-enantiomer of the anticonvulsant drug mephenytoin exhibits a genetic polymorphism in humans. This… Expand
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1996
1996
The polymorphic metabolism of S-mephenytoin and the distribution of two known deleterious mutant CYP2C19 alleles was determined… Expand
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