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Gene Deletion

Known as: Deletion, Gene, MOLPATH.DEL, Gene Deletions 
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion… 
National Institutes of Health

Related topics

Related topics

6 relations
Chromosome DeletionHBA2 gene SEA deletion:Arb:Pt:Bld:Ord:MolgenMicrodeletion syndromes:Arb:Pt:XXX:Nom:FISHY chromosome deletion:Prid:Pt:Bld/Tiss:Nom

Narrower (1)

Contiguous Abcd1-Dxs1375e Deletion Syndrome

Broader (1)

Gene Mutation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Preprotachykinin-A gene deletion protects mice against acute pancreatitis and associated lung injury.
Impaired lung function in severe acute pancreatitis is the primary cause of morbidity and mortality in this condition… 
Review
1996
Review
1996
Interstitial deletion of 11(p11.2p12): a newly described contiguous gene deletion syndrome involving the gene for hereditary multiple exostoses (EXT2).
Individuals with deletions of the proximal portion of the short arm of chromosome 11 share many manifestations including mental… 
Highly Cited
1990
Highly Cited
1990
GST1 gene deletion determined by polymerase chain reaction.
The human glutathione transferase (GST) isozyme GSTIt is frequently deficient (31-61 %) in individuals (1). The absence of GSTit… 
Highly Cited
1990
Highly Cited
1990
Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.
Familial growth hormone deficiency type 1A is an autosomal recessive disease caused by deletion of both growth hormone-1 (GH1… 
Highly Cited
1989
Highly Cited
1989
Identification of a second “French Canadian” LDL receptor gene deletion and development of a rapid method to detect both deletions
Hobbs et al. (N. Engl. J. Med. 317: 734–737, 1987) reported a large deletion of approximately 10 kilobases in the 5′ portion of… 
Highly Cited
1988
Highly Cited
1988
Loss of a highly conserved domain on p53 as a result of gene deletion during Friend virus-induced erythroleukemia.
We have investigated a mutation in the p53 gene leading to expression of a truncated 46,000-dalton protein in a Friend virus… 
Highly Cited
1987
Highly Cited
1987
P450XXI (steroid 21-hydroxylase) gene deletions are not found in family studies of congenital adrenal hyperplasia.
Congenital adrenal hyperplasia (CAH) is a common genetic disorder due to defective 21-hydroxylation of steroid hormones. The… 
Highly Cited
1985
Highly Cited
1985
Human growth hormone gene deletion without antibody formation or growth arrest during treatment--a new disease entity?
Using restriction endonuclease analysis of genomic DNA hybridized to a human chorionic somatomammotropin (hCS) complementary (c… 
Highly Cited
1983
Highly Cited
1983
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants
We have analyzed T antigens produced by a set of simian virus 40 (SV40) A gene deletion mutants for ATPase activity and for… 
Highly Cited
1982
Highly Cited
1982
A gene deletion ending at the midpoint of a repetitive DNA sequence in one form of hereditary persistence of fetal haemoglobin
The form of hereditary persistence of fetal haemoglobin (HPFH) that commonly occurs in black populations is an inherited disorder… 
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