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SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans
Lighter variations of pigmentation in humans are associated with diminished number, size, and density of melanosomes, the pigmented organelles of melanocytes. Here we show that zebrafish goldenExpand
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Allelic association of human dopamine D2 receptor gene in alcoholism.
In a blinded experiment, we report the first allelic association of the dopamine D2 receptor gene in alcoholism. From 70 brain samples of alcoholics and nonalcoholics, DNA was digested withExpand
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Radiographic analysis of zebrafish skeletal defects.
Systematic identification of skeletal dysplasias in model vertebrates provides insight into the pathogenesis of human skeletal disorders and can aid in the identification of orthologous human genes.Expand
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Zebrafish-Mycobacterium marinum model for mycobacterial pathogenesis.
We report here the development of a pathogenesis model utilizing Mycobacterium marinum infection of zebrafish (Danio rerio) for the study of mycobacterial disease. The zebrafish model mimics certainExpand
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pak2a mutations cause cerebral hemorrhage in redhead zebrafish
The zebrafish is a powerful model for studying vascular development, demonstrating remarkable conservation of this process with mammals. Here, we identify a zebrafish mutant, redhead (rhdmi149), thatExpand
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Annual fish as a genetic model for aging.
Advancement in the genetics of aging and identification of longevity genes has been largely due to the model organisms such as Caenorhabditis elegans and Drosophila melanogaster. However, knowledgeExpand
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Identification and characterization of zebrafish thrombocytes
To analyse primary haemostasis in the zebrafish we have identified and characterized the zebrafish thrombocyte by morphologic, immunologic and functional approaches. Novel methods were developed forExpand
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Demonstration of the extrinsic coagulation pathway in teleostei: Identification of zebrafish coagulation factor VII
It is not known whether the mammalian mechanism of coagulation initiation is conserved in fish. Identification of factor VII is critical in providing evidence for such a mechanism. A cDNA was clonedExpand
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Analysis of blood coagulation in the zebrafish.
The zebrafish (Danio rerio) is a unique animal model in which saturation mutagenesis has been used to identify genes involved in vertebrate development. The relevance of the zebrafish as a geneticExpand
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