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A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.
TLDR
Adjuvant chemotherapy has a significant survival benefit in patients with resected pancreatic cancer, whereas adjuvant chemoradiotherapy has a deleterious effect on survival.
IAP Guidelines for the Surgical Management of Acute Pancreatitis
TLDR
During 2002 the International Association of Pancreatology developed evidenced-based guidelines on the surgical management of acute pancreatitis, which should form the basis for audit studies in order to determine the quality of patient care delivery.
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial.
TLDR
Compared with the use of fluorouracil plus folinic acid, gemcitabine did not result in improved overall survival in patients with completely resected pancreatic cancer.
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.
TLDR
Modeling and familial clustering suggest that SPINK1 mutations are disease modifying, possibly by lowering the threshold for pancreatitis from other genetic or environmental factors, but by themselves do not cause disease.
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