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DNA Damage

Known as: Damages, DNA, DNA Injury, Damage, DNA 
Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
  • J. Hoeijmakers
  • The New England journal of medicine
  • 2009
  • Corpus ID: 205115506
NA damage has emerged as a major culprit in cancer and many diseases related to aging. The stability of the genome is supported… Expand
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Review
2003
Review
2003
Oxidative DNA damage is an inevitable consequence of cellular metabolism, with a propensity for increased levels following toxic… Expand
Highly Cited
2003
Highly Cited
2003
The function of the ATR (ataxia-telangiectasia mutated– and Rad3-related)–ATRIP (ATR-interacting protein) protein kinase complex… Expand
Review
2000
Review
2000
A major development of carcinogenesis research in the past 20 years has been the discovery of significant levels of DNA damage… Expand
Highly Cited
2000
Highly Cited
2000
BACKGROUND The response of eukaryotic cells to double-strand breaks in genomic DNA includes the sequestration of many factors… Expand
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Highly Cited
1998
Highly Cited
1998
After DNA damage, many cells appear to enter a sustained arrest in the G2 phase of the cell cycle. It is shown here that this… Expand
Highly Cited
1997
Highly Cited
1997
DNA-damaging agents signal to p53 through as yet unidentified posttranscriptional mechanisms. Here we show that phosphorylation… Expand
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Highly Cited
1991
Highly Cited
1991
The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could… Expand
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Highly Cited
1988
Highly Cited
1988
Human lymphocytes were either exposed to X-irradiation (25 to 200 rads) or treated with H2O2 (9.1 to 291 microM) at 4 degrees C… Expand
Review
1988
Review
1988
A major portion of the toxicity of hydrogen peroxide in Escherichia coli is attributed to DNA damage mediated by a Fenton… Expand