Comet Assay

Known as: Gel Electrophoreses, Single-Cell, Assays, Comet, Electrophoresis, Single-Cell Gel 
A rapid, simple, visual and sensitive technique for measuring DNA breakage in individual mammalian cells in response to a test agent. A cell is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
05010015019962018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Reactive species such as free radicals are constantly generated in vivo and DNA is the most important target of oxidative stress… (More)
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2011
2011
The comet assay is a sensitive electrophoretic method for measuring DNA breaks at the level of single cells, used widely in… (More)
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2010
2010
The alkaline single cell gel electrophoresis (comet) assay has become a widely used method for the detection of DNA damage and… (More)
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2010
2010
Although the Comet assay, a procedure for quantitating DNA damage in mammalian cells, is considered sensitive, it has never been… (More)
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2004
2004
The authors investigated whether a potential radioprotective effect of amifostine (WR-2721) after in vitro or in vivo… (More)
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2004
2004
The single cell gel electrophoresis (SCGE) assay, also known as the Comet assay, is one of the most promising genotoxicity tests… (More)
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2001
2001
In recent years the Comet assay (or single cell gel electrophoresis assay) has been established as a rapid and sensitive method… (More)
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2001
2001
Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure and cancer susceptibility. Patient… (More)
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2001
2001
Single stranded DNA breaks induced by Zinc sulfate in mice has been studied in vivo using Alkaline Single Cell Gel… (More)
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1999
1999
The “comet assay” has become an interesting and a very useful tool for the analysis of the induction and amount of DNA damage in… (More)
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