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Comet Assay

Known as: Gel Electrophoreses, Single-Cell, Assays, Comet, Electrophoresis, Single-Cell Gel 
A rapid, simple, visual and sensitive technique for measuring DNA breakage in individual mammalian cells in response to a test agent. A cell is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Silver nanoparticles (Ag-np) are being used increasingly in wound dressings, catheters, and various household products due to… Expand
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Review
2008
Review
2008
The comet assay is a versatile and sensitive method for measuring single- and double-strand breaks in DNA. The mechanism of… Expand
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Highly Cited
2006
Highly Cited
2006
We present a procedure for the comet assay, a gel electrophoresis–based method that can be used to measure DNA damage in… Expand
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Review
2004
Review
2004
The comet assay (single-cell gel electrophoresis) is a simple method for measuring deoxyribonucleic acid (DNA) strand breaks in… Expand
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Highly Cited
2003
Highly Cited
2003
The single-cell gel electrophoresis, also known as the comet assay, has gained wide-spread popularity as a simple and reliable… Expand
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Highly Cited
2002
Highly Cited
2002
We determined the genotoxicity of 39 chemicals currently in use as food additives. They fell into six categories-dyes, color… Expand
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Highly Cited
2000
Highly Cited
2000
Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel… Expand
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Highly Cited
1997
Highly Cited
1997
A range of applications of the alkaline comet assay is covered, from investigations of the physicochemical behaviour of DNA… Expand
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Highly Cited
1997
Highly Cited
1997
The comet assay (single-cell gel electrophoresis), which measures DNA strand breaks at the level of single cells, is very easily… Expand
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Highly Cited
1990
Highly Cited
1990
A method for measuring DNA damage to individual cells, based on the technique of microelectrophoresis, was described by Ostling… Expand
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