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Alkaline Comet Assay

Known as: Alkaline Single-Cell Gel Electrophoresis Assay, Comet Assays, Alkaline, Assay, Alkaline Comet 
National Institutes of Health

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Comet Assay

Papers overview

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2014
2014
Micropatterned comet assay enables high throughput and sensitive DNA damage quantification.
The single cell gel electrophoresis assay, also known as the comet assay, is a versatile method for measuring many classes of DNA… 
Highly Cited
2012
Highly Cited
2012
Alkaline and neutral Comet assay profiles of sperm DNA damage in clinical groups.
BACKGROUND The analysis of sperm DNA fragmentation has become a new marker to predict male infertility, and many techniques have… 
Highly Cited
2010
Highly Cited
2010
Combinations of DNA Methyltransferase and Histone Deacetylase Inhibitors Induce DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance with IFN-Stimulated Gene Expression
Because epigenetic inhibitors can reduce cancer cell proliferation, we tested the hypothesis that concurrent inhibition of… 
Review
2009
Review
2009
Environmental and occupational biomonitoring using the Comet assay.
Highly Cited
2003
Highly Cited
2003
Measurements using the alkaline comet assay predict bladder cancer cell radiosensitivity
In the UK, the two main treatments of invasive bladder cancer are radiotherapy or cystectomy. However, ∼50% of patients… 
Highly Cited
2003
Highly Cited
2003
Heme Oxygenase-1 Gene Expression Attenuates Angiotensin II-Mediated DNA Damage in Endothelial Cells
Heme oxygenase (HO) catalyzes the conversion of heme to biliverdin with the release of iron and carbon monoxide. HO-1 is… 
2003
2003
Potential use of the alkaline comet assay as a predictor of bladder tumour response to radiation
Bladder tumours show a variable response to radiotherapy with only about 50% showing good local control; currently there is no… 
Highly Cited
2002
Highly Cited
2002
Assessment of genome damage in a population of Croatian workers employed in pesticide production by chromosomal aberration analysis, micronucleus assay and Comet assay
The widespread use of pesticides suggests that the evaluation of their genotoxicity should be extended using the different assays… 
Highly Cited
1998
Highly Cited
1998
An examination of DNA strand breakage in the comet assay and antioxidant capacity in diabetic patients.
Highly Cited
1974
Highly Cited
1974
Energy source for comet outbursts
A COMET nucleus is generally recognised as an icy conglomerate, as was originally proposed by Whipple1. The Orbiting Astronomical… 
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