In Situ Nick-End Labeling

Known as: Nick-End Labeling, In Situ, Nick End-Labeling, In Situ, In Situ Nick End Labeling 
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in… (More)
National Institutes of Health

Related topics

Related topics

4 relations
ApoptosisComet Assaystandards characteristics

Broader (1)

Genetic Techniques

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Self-organizing optic-cup morphogenesis in three-dimensional culture
s / Neuroscience Research 71S (2011) e108–e415 e127 P2-e02 Generation of neural crest progenitor cells from human induced… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Whole-brain anatomical networks: Does the choice of nodes matter?
Whole-brain anatomical connectivity in living humans can be modeled as a network with diffusion-MRI and tractography. Network… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome
The ability to derive a whole-genome map of transcription-factor binding sites (TFBS) is crucial for elucidating gene regulatory… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2000
2000
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy.
Situ Nick End-Labeling (TUNEL) in Hearts With Dilated Cardiomyopathy To the Editor: Recently, Kanoh et al 1 seriously questioned… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair.
BACKGROUND The presence of apoptotic myocytes has been reported in human hearts with dilated cardiomyopathy (DCM) on the basis of… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction.
OBJECTIVES The purpose of this study was to determine whether apoptosis is a major mechanism of cell death in patients with… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum.
Cellular stress, particularly in response to toxic and metabolic insults that perturb function of the endoplasmic reticulum (ER… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases.
In cancer metastasis, only a small percentage of cells released from a primary tumor successfully form distant lesions, but it is… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
In situ apoptotic cell labeling by the TUNEL method: improvement and evaluation on cell preparations.
TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling) is a method of choice for rapid identification and… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note.
Detection of DNA fragments in situ using the terminal deoxyribonucleotidyl transferase (TDT)-mediated dUTP-digoxigenin nick end… (More)
Is this relevant?