Genotoxic Stress

Known as: Genotoxic Stresses, Stress, Genotoxic, Stresses, Genotoxic 
Exposure to DNA-damaging agents and subsequent energy expenditures by a cell to repair DNA damage. Genotoxic stress elicits biochemical responses… (More)
National Institutes of Health

Papers overview

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Review
2013
Review
2013
The protein kinase ataxia-telangiectasia mutated (ATM) is best known for its role as an apical activator of the DNA damage… (More)
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Highly Cited
2013
Highly Cited
2013
Loss of function of the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) tumor suppressor gene is associated with… (More)
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Highly Cited
2011
Highly Cited
2011
A better understanding of the mechanisms through which anticancer drugs exert their effects is essential to improve combination… (More)
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Highly Cited
2009
Highly Cited
2009
(Cell 134, 451–460; August 8, 2008) It has been brought to our attention that some of the figures in our paper did not properly… (More)
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Highly Cited
2009
Highly Cited
2009
Mutations in BRCA1 are associated with a high risk of breast and ovarian cancer. BRCA1 participates in the DNA damage response… (More)
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Highly Cited
2008
Highly Cited
2008
Cellular senescence suppresses cancer by arresting cell proliferation, essentially permanently, in response to oncogenic stimuli… (More)
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Highly Cited
2006
Highly Cited
2006
XPF–ERCC1 endonuclease is required for repair of helix-distorting DNA lesions and cytotoxic DNA interstrand crosslinks. Mild… (More)
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Highly Cited
2004
Highly Cited
2004
Apoptosis is triggered by activation of initiator caspases upon complex-mediated clustering of the inactive zymogen, as occurs in… (More)
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Highly Cited
2003
Highly Cited
2003
The transcription factor NF-kappaB is critical for setting the cellular sensitivities to apoptotic stimuli, including DNA… (More)
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Highly Cited
1996
Highly Cited
1996
GENOTOXIC stress triggers signalling pathways that mediate either the protection or killing of affected cells. Whereas induction… (More)
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