DNA Repair

Known as: DNA Damage Repair, Deoxyribonucleic acid repair, Unscheduled DNA Synthesis 
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair… (More)

Topic mentions per year

Topic mentions per year

1957-2018
01000200019572017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Prostate cancer (PCa) is the most widely diagnosed male cancer in the Western World and while low- and intermediate-risk PCa… (More)
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Review
2016
Review
2016
Genomic mutations caused by cytotoxic agents used in cancer chemotherapy may cause secondary malignancies as well as contribute… (More)
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Review
2015
Review
2015
The metabolism of NAD has emerged as a key regulator of cellular and organismal homeostasis. Being a major component of both… (More)
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Highly Cited
2006
Highly Cited
2006
Ionizing radiation represents the most effective therapy for glioblastoma (World Health Organization grade IV glioma), one of the… (More)
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Highly Cited
2005
Highly Cited
2005
BRCA1 and BRCA2 are important for DNA double-strand break repair by homologous recombination, and mutations in these genes… (More)
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Highly Cited
2003
Highly Cited
2003
Most human somatic cells can undergo only a limited number of population doublings in vitro. This exhaustion of proliferative… (More)
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Highly Cited
2002
Highly Cited
2002
The RAD6 pathway is central to post-replicative DNA repair in eukaryotic cells; however, the machinery and its regulation remain… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The response of eukaryotic cells to double-strand breaks in genomic DNA includes the sequestration of many factors… (More)
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Highly Cited
1999
Highly Cited
1999
Germline mutations in BRCA1 confer a high risk of breast and ovarian tumors. The role of BRCA1 in tumor suppression is not yet… (More)
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Highly Cited
1988
Highly Cited
1988
Human lymphocytes were either exposed to X-irradiation (25 to 200 rads) or treated with H2O2 (9.1 to 291 microM) at 4 degrees C… (More)
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