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DNA Repair
Known as:
DNA Damage Repair
, Deoxyribonucleic acid repair
, Unscheduled DNA Synthesis
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair…
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National Institutes of Health
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Related topics
Related topics
50 relations
APEX1 protein, human
APEX2 gene
APITD1 gene
ATR gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Homologous recombination in DNA repair and DNA damage tolerance
Xuan Li
,
W. Heyer
Cell Research
2008
Corpus ID: 205126554
Homologous recombination (HR) comprises a series of interrelated pathways that function in the repair of DNA double-stranded…
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Highly Cited
2006
Highly Cited
2006
DNA Repair and Mutagenesis
E. Friedberg
,
G. Walker
,
W. Siede
2006
Corpus ID: 82247704
DNA damage Mutations The reversal of base damage Base excision repair Nucleotide excision repair in prokaryotes Nucleotide…
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Highly Cited
2006
Highly Cited
2006
DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy.
K. Olaussen
,
A. Dunant
,
+13 authors
J. Soria
New England Journal of Medicine
2006
Corpus ID: 24924323
BACKGROUND Adjuvant cisplatin-based chemotherapy improves survival among patients with completely resected non-small-cell lung…
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Highly Cited
2005
Highly Cited
2005
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
H. Farmer
,
N. Mccabe
,
+11 authors
A. Ashworth
Nature
2005
Corpus ID: 4364706
BRCA1 and BRCA2 are important for DNA double-strand break repair by homologous recombination, and mutations in these genes…
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Review
2004
Review
2004
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
A. Sancar
,
L. Lindsey-Boltz
,
K. Unsal-Kaçmaz
,
S. Linn
Annual Review of Biochemistry
2004
Corpus ID: 38131471
DNA damage is a relatively common event in the life of a cell and may lead to mutation, cancer, and cellular or organismic death…
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Highly Cited
2002
Highly Cited
2002
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
C. Hoege
,
B. Pfander
,
George-Lucian Moldovan
,
George Pyrowolakis
,
S. Jentsch
Nature
2002
Corpus ID: 205209495
The RAD6 pathway is central to post-replicative DNA repair in eukaryotic cells; however, the machinery and its regulation remain…
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Review
2002
Review
2002
Polymorphisms in DNA repair genes and associations with cancer risk.
E. Goode
,
C. Ulrich
,
J. Potter
Cancer Epidemiology, Biomarkers and Prevention
2002
Corpus ID: 20458430
Common polymorphisms in DNA repair genes may alter protein function and an individual's capacity to repair damaged DNA; deficits…
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Highly Cited
2001
Highly Cited
2001
Human DNA Repair Genes
R. Wood
,
M. Mitchell
,
J. Sgouros
,
T. Lindahl
Science
2001
Corpus ID: 17375001
Cellular DNA is subjected to continual attack, both by reactive species inside cells and by environmental agents. Toxic and…
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Review
1999
Review
1999
Quality control by DNA repair.
T. Lindahl
,
R. Wood
Science
1999
Corpus ID: 46196721
Faithful maintenance of the genome is crucial to the individual and to species. DNA damage arises from both endogenous sources…
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Review
1993
Review
1993
Instability and decay of the primary structure of DNA
T. Lindahl
Nature
1993
Corpus ID: 4283694
Although DNA is the carrier of genetic information, it has limited chemical stability. Hydrolysis, oxidation and nonenzymatic…
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