ATR gene

Known as: SCKL1, ATAXIA-TELANGIECTASIA AND RAD3-RELATED, MEC1 
This gene is involved in cell cycle checkpoints and DNA recombination.

Topic mentions per year

Topic mentions per year

1967-2018
0204019672018

Papers overview

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Highly Cited
2013
Highly Cited
2013
ATR, activated by replication stress, protects replication forks locally and suppresses origin firing globally. Here, we show… (More)
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Highly Cited
2008
Highly Cited
2008
Large brain size is one of the defining characteristics of modern humans. Seckel syndrome (MIM 210600), a disorder of markedly… (More)
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Highly Cited
2007
Highly Cited
2007
Developmental abnormalities, cancer, and premature aging each have been linked to defects in the DNA damage response (DDR… (More)
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Highly Cited
2006
Highly Cited
2006
Telomeres protect chromosome ends from being detected as lesions and from triggering DNA damage checkpoints. Paradoxically… (More)
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Highly Cited
2005
Highly Cited
2005
The perception of downy mildew avirulence (Arabidopsis thaliana Recognized [ATR]) gene products by matching Arabidopsis thaliana… (More)
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Highly Cited
2004
Highly Cited
2004
Timing of DNA replication initiation is dependent on S-phase-promoting kinase (SPK) activity at discrete origins and the… (More)
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Highly Cited
2001
Highly Cited
2001
Eukaryotic cells respond to DNA damage by arresting the cell cycle and modulating gene expression to ensure efficient DNA repair… (More)
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Highly Cited
2000
Highly Cited
2000
Checkpoints of DNA integrity are conserved throughout evolution, as are the kinases ATM (Ataxia Telangiectasia mutated) and ATR… (More)
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Highly Cited
1996
Highly Cited
1996
Mutants of the Saccharomyces cerevisiae ataxia telangiectasia mutated (ATM) homolog MEC1/SAD3/ESR1 were identified that could… (More)
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Highly Cited
1995
Highly Cited
1995
We demonstrate that in S. cerevisiae the rate of ongoing S phase is slowed when the DNA is subjected to alkylation. Slowing of… (More)
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