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ATR gene
Known as:
SCKL1
, ATAXIA-TELANGIECTASIA AND RAD3-RELATED
, MEC1
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This gene is involved in cell cycle checkpoints and DNA recombination.
National Institutes of Health
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Related topics
Related topics
12 relations
ANTXR2 gene
ATR protein, human
Cell Cycle Control
DNA Repair
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ATR wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Einfluss der Struktur von Aluminium-Metaphosphaten auf die chemische Härtung von Kalium-Wasserglas-Bindern
A. Alavi
2019
Corpus ID: 181715837
In dieser Arbeit wurden erstmals die strukturelle Wechselwirkung zwischen Kalium- Wasserglas-Systemen mit Aluminium…
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2017
2017
Ataxia Telangiectasia Mutated and Rad 3 Related ( ATR ) Protein Kinase Inhibition Is Synthetically Lethal in XRCC 1 Deficient Ovarian Cancer Cells
R. Sultana
,
T. Abdel-Fatah
,
+6 authors
S. Madhusudan
2017
Corpus ID: 51090238
Introduction: Ataxia telangiectasia mutated and Rad3 Related (ATR) protein kinase is a key sensor of single-stranded DNA…
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2016
2016
Abstract CT012: Phase 1 trial of first-in-class ATR inhibitor VX-970 in combination with cisplatin (Cis) in patients (pts) with advanced solid tumors (NCT02157792)
G. Shapiro
,
R. Wesolowski
,
+12 authors
T. Yap
2016
Corpus ID: 57082245
Background: ATR is a regulator of the cellular response to replication stress, where it signals DNA damage repair through the…
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2014
2014
ATR Inhibition Exacerbates Replication Stress in TP53 or ATM Deficient CLL Cells and Enhances Sensitivity to Chemotherapy and Targeted Therapy
M. Kwok
,
N. Davies
,
+6 authors
T. Stankovic
2014
Corpus ID: 208431643
DNA damage response (DDR) defects, particularly TP53 or biallelic ATM aberrations, are associated with chemoresistance in chronic…
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2014
2014
Hsp 90 Inhibitor Geldanamycin Enhances the Antitumor Efficacy of Enediyne Lidamycin in Association with Reduced DNA Damage Repair
Fei Han
,
Liang Li
,
Bo-yang Shang
,
R. Shao
,
Yong-su Zhen
2014
Corpus ID: 38089743
DNA repair enables tumor cells to survive from DNA damage induced by chemotherapeutic treatments or ionizing radiation (IR), and…
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2011
2011
SET 8 is degraded via PCNA-coupled CRL 4 ( CDT 2 ) ubiquitylation in S phase and after UV irradiation
Stine Jørgensen
,
M. Eskildsen
,
+8 authors
C. Sørensen
2011
Corpus ID: 170077505
Eukaryotic cell cycle progression requires faithful DNA duplication and division of the chromosomes between daughter cells. These…
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2007
2007
Ku70/80 modulates ATM and ATR signaling pathways in response to DNA double-strand breaks
富松 望
2007
Corpus ID: 87712626
2004
2004
Nonhomologous End Joining Homologous Recombination Repair but Independent of ATR Affecting Cell Radiosensitivity Is Dependent on Updated
Hongyan Wang
,
Huichen Wang
,
S. Powell
,
G. Iliakis
,
Ya Wang
2004
Corpus ID: 15523443
ATR is one of the most important checkpoint proteins in mammalian cells responding to DNA damage. Cells defective in normal ATR…
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2002
2002
Untersuchungen zur Pflanzenschutzmittelanlagerung in Obstanlagen bei grob- und feintropfiger Applikation
H. Knewitz
,
H. Koch
,
G. Fleischer
,
Friedrich Lehn
Gesunde Pflanzen
2002
Corpus ID: 32042684
Zusammenfassung:In elf Versuchen wurde das Anlagerungsverhalten bei grob- und feintropfiger Applikation in Apfelanlagen…
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1981
1981
[Inhibitory action of urogastrone from pregnant horses urine on gastric acid secretion (author's transl)].
T. Yamaura
,
N. Umehara
,
K. Takenaga
,
T. Numoto
,
K. Tosaka
Nihon yakurigaku zasshi. Folia pharmacologica…
1981
Corpus ID: 12163908
Inhibitory actions of urogastrone (UG) on gastric acid secretion induced by tetragastrin (TG), histamine (Hist) and carbachol…
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