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Protein Degradation, Regulatory

Known as: Protein Degradation Process, protein breakdown, protein catabolism 
Specific degradation of a protein - involving conjugation, transport, oxidation, and proteolysis - involved in signal transduction or cell… 
National Institutes of Health

Related topics

Related topics

49 relations
CUL1 geneCUL2 geneCUL3 geneCUL4B gene

Narrower (3)

Protein DenaturationProteolysismitochondrial protein catabolic process

Broader (1)

protein metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Sphingolipid functions in Saccharomyces cerevisiae.
Highly Cited
1999
Highly Cited
1999
Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown.
Review
1992
Review
1992
The mechanism and functions of ATP-dependent proteases in bacterial and animal cells.
In eukaryotes and prokaryotes, the degradation of most cell proteins requires metabolic energy (Goldberg and St. John, 1976… 
Highly Cited
1988
Highly Cited
1988
Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo
Review
1988
Review
1988
Ubiquitin-mediated protein degradation.
Highly Cited
1985
Highly Cited
1985
Insulin-mediated reduction of whole body protein breakdown. Dose-response effects on leucine metabolism in postabsorptive men.
In vivo effects of insulin on plasma leucine and alanine kinetics were determined in healthy postabsorptive young men (n = 5… 
Highly Cited
1982
Highly Cited
1982
Relationship of plasma leucine and alpha-ketoisocaproate during a L-[1-13C]leucine infusion in man: a method for measuring human intracellular leucine tracer enrichment.
Highly Cited
1981
Highly Cited
1981
Effect of exercise on protein turnover in man.
1. We have investigated the effects of moderate long-term exercise on protein turnover in fed man by measuring the extent of… 
Highly Cited
1980
Highly Cited
1980
Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.
The heat-stable polypeptide ATP-dependent proteolysis factor 1 (APF-1) of the reticulocyte proteolytic system forms covalent… 
Highly Cited
1974
Highly Cited
1974
Origin and possible significance of alanine production by skeletal muscle.
Abstract These experiments were undertaken to determine the source of alanine released by skeletal muscle and to clarify the… 
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