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CUL4B gene

Known as: CULLIN 4B, CUL4B, Cullin 4B Gene 
This gene plays a role in the regulation of ubiquitination.
National Institutes of Health

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Related topics

5 relations
CUL4A geneCullin-4BProtein Degradation, RegulatoryUbiquitination

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CUL4B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
CUL4B promotes metastasis and proliferation in pancreatic cancer cells by inducing epithelial‐mesenchymal transition via the Wnt/β‐catenin signaling pathway
This study determines whether cullin 4B (CUL4B) promotes pancreatic cancer (PC) metastasis by inducing epithelial‐mesenchymal… 
2018
2018
MicroRNA-133b inhibits cell proliferation and promotes apoptosis by targeting cullin 4B in esophageal squamous cell carcinoma
microRNAs (miRs) serve a role as modulators during carcinogenesis. It has been demonstrated that the expression of miR-133b is… 
2018
2018
Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells
The major aim of the present study was to explore the effects of cullin 4B (CUL4B) on the proliferation and invasion of human… 
2017
2017
Cul4B is a novel prognostic marker in cholangiocarcinoma
Cullin 4B (Cul4B), a scaffold protein that assembles the ubiquitin ligase complex, is involved in a wide variety of physiological… 
2016
2016
Lack of CUL 4 B in adipocytes promotes PPARγ-mediated adipose tissue expansion and insulin sensitivity Running title : CUL 4 B negatively regulates PPARγ
2015
2015
Decreased CUL 4 B expression inhibits malignant proliferation of glioma in vitro and in vivo
– OBJECTIVE: Cullin 4B (CUL4B) is a component of the Cullin 4B-Ring E3 ligase complex (CRL4B) that plays a role in proteolysis… 
2015
2015
Knockdown of CUL 4 B inhibits proliferation and promotes apoptosis of colorectal cancer cells through suppressing the Wnt / β-catenin signaling pathway
Colorectal cancer is one of the leading causes of cancer related deaths worldwide. Cullin 4B (CUL4B) is over-expressed in diverse… 
2014
2014
CRL4B interacts with and coordinates the SIN3A-HDAC complex to repress CDKN1A and drive cell cycle progression
ABSTRACT CUL4B, a scaffold protein that assembles the CRL4B ubiquitin ligase complex, participates in the regulation of a broad… 
Highly Cited
2010
Highly Cited
2010
Deletion of the CUL4B gene in a boy with mental retardation, minor facial anomalies, short stature, hypogonadism, and ataxia
The CUL4B gene encodes a member of Cullin–RING ubiquitin ligase complex. Point mutations in CUL4B were identified recently in… 
2007
2007
Microscopy: Tip-top imaging
Images of nanoscale structures can be constructed using the flow of electrons ejected from a metal probe tip by a fast laser… 
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