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Proteolysis

Known as: Degradations, Protein, Degradation, Protein, Protein Degradations 
Proteolysis typically involves hydrolysis of specific peptide bond(s) with formation of smaller polypeptides in a target protein during maturation or… 
National Institutes of Health

Related topics

Related topics

50 relations
ADAM12 wt AlleleADAM15 geneADAM17 wt AlleleADAMTS13 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Mutations in PINK1 or Parkin lead to familial parkinsonism. The authors suggest that PINK1 and Parkin form a pathway that senses… 
Highly Cited
2006
Highly Cited
2006
Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis.
Cell migration on 2D surfaces is governed by a balance between counteracting tractile and adhesion forces. Although biochemical… 
Highly Cited
2003
Highly Cited
2003
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
Rho family GTPases regulate the cytoskeleton and cell migration and are frequently overexpressed in tumours. Here, we identify… 
Review
2001
Review
2001
Glutamate uptake
  • N. Danbolt
  • Progress in neurobiology
  • 2001
  • Corpus ID: 27347413
Review
2000
Review
2000
Ubiquitin‐mediated proteolysis: biological regulation via destruction
The ubiquitin proteolytic system plays an important role in a broad array of basic cellular processes. Among these are regulation… 
Highly Cited
1999
Highly Cited
1999
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.
The unfolded protein response (UPR) controls the levels of molecular chaperones and enzymes involved in protein folding in the… 
Review
1997
Review
1997
Caspases: Intracellular Signaling by Proteolysis
Highly Cited
1996
Highly Cited
1996
Lamin proteolysis facilitates nuclear events during apoptosis
Expression of the adenovirus E1A oncogene stimulates both cell proliferation and p53-dependent apoptosis in rodent cells. p53… 
Highly Cited
1995
Highly Cited
1995
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
I kappa B-alpha inhibits transcription factor NF-kappa B by retaining it in the cytoplasm. Various stimuli, typically those… 
Highly Cited
1977
Highly Cited
1977
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.
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