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ADAMTS13 gene

Known as: DKFZp434C2322, VON WILLEBRAND FACTOR-CLEAVING PROTEASE, ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 13 Gene 
This gene plays a role in von Willebrand factor function.
National Institutes of Health

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ADAMTS12 geneADAMTS13 ProteinADAMTS13 protein, humanBlood coagulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Role of ADAMTS13 in diet-induced liver steatosis.
Previous studies, predominantly based on increased or decreased plasma levels, have reported conflicting data on a potential… 
2015
2015
Probing ADAMTS13 Substrate Specificity using Phage Display
Von Willebrand factor (VWF) is a large, multimeric protein that regulates hemostasis by tethering platelets to the subendothelial… 
2015
2015
Adult-onset congenital thrombotic thrombocytopenic purpura caused by a novel compound heterozygous mutation of the ADAMTS13 gene
Abstract Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease, characterized by microangiopathic hemolytic… 
2014
2014
Carboxyl Terminus of ADAMTS13 Directly Inhibits Platelet Aggregation and Ultra Large von Willebrand Factor String Formation Under Flow in a Free-Thiol–Dependent Manner
Objective—ADAMTS13 (A Disintegrin And Metalloprotease with Thrombospondin type 1 repeats, 13) cleaves von Willebrand factor (VWF… 
2013
2013
C2362F mutation gives rise to an ADAMTS13-resistant von Willebrand factor
Summary von Willebrand factor (VWF) multimers result from proteolysis by the metalloprotease ADAMTS13. Since C2362F-VWF features… 
2012
2012
Identification of epitopes on ADAMTS13 recognized by a panel of monoclonal antibodies with functional or non-functional effects on catalytic activity.
2010
2010
Expression of terminal 2-6 – linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS 13 *
1Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity… 
2009
2009
ADAMTS13 and von Willebrand factor concentrations in patients with diabetes mellitus
The von Willebrand factor (VWF) is elevated in patients with diabetes mellitus and degraded by a metalloprotease, ADAMTS13. We… 
2008
2008
Clinical insights from observations on ADAMTS13 deficiency in liver cirrhosis
Thromb Haemost 2008; 99: 987–988 Ten years ago ADAMTS13 (A disintegrin and metalloprotease with thrombospondin 1-like repeats… 
2005
2005
[Identification of two novel mutations in ADAMTS13 gene in a patient with hereditary thrombotic thrombocytopenic purpura].
OBJECTIVE To investigate the gene mutations of ADAMTS13 in a highly suspected hereditary thrombocytopenic purpura (TTP) patient… 
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