ADAMTS13 gene

Known as: DKFZp434C2322, VON WILLEBRAND FACTOR-CLEAVING PROTEASE, ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 13 Gene 
This gene plays a role in von Willebrand factor function.
National Institutes of Health

Papers overview

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2013
2013
Complement dysregulation leads to atypical hemolytic uremic syndrome (aHUS), while ADAMTS13 deficiency causes thrombotic… (More)
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2010
2010
Reperfusion after brain ischemia causes thrombus formation and microcirculatory disturbances, which are dependent on the platelet… (More)
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Highly Cited
2008
Highly Cited
2008
We examined the role of N-linked glycan structures of VWF on its interaction with ADAMTS13. PNGase F digestion followed by lectin… (More)
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Highly Cited
2007
Highly Cited
2007
Von Willebrand factor (VWF) mediates the tethering/adhesion of platelets at sites of vascular injury. This function depends on… (More)
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Highly Cited
2006
Highly Cited
2006
The metalloprotease ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) cleaves highly… (More)
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Highly Cited
2006
Highly Cited
2006
Deficiency of ADAMTS13 is found in patients with thrombotic thrombocytopenic purpura (TTP), and the genetic defects in the… (More)
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Highly Cited
2005
Highly Cited
2005
Although the chromosomal localization (9q34) of the gene encoding the human form of ADAMTS13 (a disintegrin-like and… (More)
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Highly Cited
2005
Highly Cited
2005
Autoantibodies neutralizing human ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif), the… (More)
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Highly Cited
2004
Highly Cited
2004
The multimeric size and the function of circulating von Willebrand factor are modulated via its proteolytic cleavage by the… (More)
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Highly Cited
2002
Highly Cited
2002
von Willebrand factor (VWF) is synthesized primarily in vascular endothelial cells and secreted into the plasma as unusually… (More)
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