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ADAMTS13 gene

Known as: DKFZp434C2322, VON WILLEBRAND FACTOR-CLEAVING PROTEASE, ADAM Metallopeptidase With Thrombospondin Type 1 Motif, 13 Gene 
This gene plays a role in von Willebrand factor function.
National Institutes of Health

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8 relations
ADAMTS12 geneADAMTS13 ProteinADAMTS13 protein, humanBlood coagulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Exploring the "minimal" structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering.
Human ADAMTS13 is a multidomain protein with metalloprotease (M), disintegrin-like (D), thrombospondin-1 (T), Cys-rich (C), and… 
2015
2015
miR-525-5p inhibits ADAMTS13 and is correlated with Ischemia/reperfusion injury-induced neuronal cell death.
The understanding of molecular mechanism underlying ischemia/reperfusion-induced neuronal death and neurological dysfunction may… 
2014
2014
Carboxyl Terminus of ADAMTS13 Directly Inhibits Platelet Aggregation and Ultra Large von Willebrand Factor String Formation Under Flow in a Free-Thiol–Dependent Manner
Objective—ADAMTS13 (A Disintegrin And Metalloprotease with Thrombospondin type 1 repeats, 13) cleaves von Willebrand factor (VWF… 
Review
2014
Review
2014
Interactions of von Willebrand factor and ADAMTS13 in von Willebrand disease and thrombotic thrombocytopenic purpura
Summary The function of von Willebrand factor (VWF), a huge multimeric protein and a key factor in platelet dependent primary… 
2013
2013
Simvastatin increases ADAMTS13 expression in podocytes.
Review
2013
Review
2013
The emerging concept of residual ADAMTS13 activity in ADAMTS13-deficient thrombotic thrombocytopenic purpura.
2010
2010
Expression of terminal 2-6 – linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS 13 *
1Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James’s Hospital, Trinity… 
2009
2009
ADAMTS13 and von Willebrand factor concentrations in patients with diabetes mellitus
The von Willebrand factor (VWF) is elevated in patients with diabetes mellitus and degraded by a metalloprotease, ADAMTS13. We… 
2007
2007
Plasma Levels of ADAMTS13 Antigen Determined with an Enzyme Immunoassay Using a Neutralizing Monoclonal Antibody Parallel ADAMTS13 Activity Levels
Measurements of plasma ADAMTS13 activity (ADAMTS13: AC) have been used for the diagnosis of patients with thrombotic… 
Review
2006
Review
2006
ADAMTS13 and microvascular thrombosis
Interaction between platelet and von Willebrand factor, a circulating adhesive glycoprotein, is essential for hemostasis under… 
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