Skip to search formSkip to main contentSkip to account menu

ADAMTS13 Protein

Known as: ADAMTS-13 Protein, A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 Protein, ADAMTS13 Protease 
An ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in… 
National Institutes of Health

Related topics

Related topics

9 relations
ADAMTS13 geneIn BloodProcess of secretionantagonists & inhibitors

Narrower (1)

ADAMTS13 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Simvastatin increases ADAMTS13 expression in podocytes.
Review
2012
Review
2012
Efficacy of rituximab in acute refractory or chronic relapsing non-familial idiopathic thrombotic thrombocytopenic purpura: a systematic review with pooled data analysis
Idiopathic thrombotic thrombocytopenic purpura (TTP) occurs primarily due to the formation of autoantibody against ADAMTS13, a… 
2007
2007
Characterization of the human β-secretase 2 (BACE2) 5′-flanking region
The main characteristic of Alzheimer's disease (AD) is brain deposition of the β-amyloid (Aβ) peptide, generated… 
2002
2002
Deficiency of von Willebrand factor-cleaving protease activity in the plasma of malignant patients.
2002
2002
[Hemolytic uremic syndrome and thrombotic thrombocytopenic purpura].
Hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are thrombotic microangiopathies (TMA). Both… 
2002
2002
Complete Defect in vWF-cleaving Protease Activity Associated with Increased Shear-induced Platelet Aggregation in Thrombotic Microangiopathy
Summary Von Willebrand factor (vWF) cleaving metalloprotease activity represents an important factor in understanding the… 
Review
2002
Review
2002
Control of von Willebrand factor multimer size and implications for disease.
2002
2002
Late Response to Cyclosporine in Refractory Thrombotic Thrombocytopenic Purpura
Plasma exchange (PEX) with fresh frozen plasma, usually in association with steroid therapy, has been shown to be the firstline… 
Review
2000
Review
2000
Thrombotic thrombocytopenic purpura: new insights in disease pathogenesis and therapy.
Summary The identification of vWF-cleaving protease and its central role in normal vWF plasma processing has led us to a new… 
Review
2000
Review
2000
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)