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Proliferating Cell Nuclear Antigen

Known as: Proliferating Cell Nuclear Antigen [Chemical/Ingredient], Cyclin, PCNA 
Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading… 
National Institutes of Health

Related topics

Related topics

29 relations
Cell CycleCell Cycle ControlDNA RepairDNA Replication

Broader (3)

Cell Cycle ProteinsCyclinsNuclear Proteins

Narrower (9)

Cyclin ACyclin BCyclin B1PCNA1 antigen, Arabidopsis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Hematopoietic Progenitor Cells and Cellular Microenvironment: Behavioral and Molecular Changes upon Interaction
Cell–cell contact between stem cells and cellular determinants of the microenvironment plays an essential role in controlling… 
Highly Cited
1997
Highly Cited
1997
Human T-cell leukemia virus type 1 Tax transactivates the human proliferating cell nuclear antigen promoter
The human T-cell leukemia virus type 1 (HTLV-1) transforming protein, Tax, is a potent transactivator of both viral and cellular… 
Highly Cited
1997
Highly Cited
1997
The prepubertal testis (prenatal and postnatal): its relationship to intratubular germ cell neoplasia: a combined Pediatric Oncology Group and Children's Cancer Study Group.
Highly Cited
1994
Highly Cited
1994
Prognostic significance of proliferating cell nuclear antigen expression in hepatocellular carcinoma
Background. Proliferating cell nuclear antigen (PCNA) is a nuclear protein synthesized in G1/S‐phase of the cell cycle and… 
Highly Cited
1994
Highly Cited
1994
DNA polymerase delta is involved in the cellular response to UV damage in human cells.
Highly Cited
1993
Highly Cited
1993
The prognostic value of immunohistochemical staining for proliferating cell nuclear antigen in synovial sarcoma
Background. The biologic behavior of synovial sarcoma remains a matter of controversy. Some investigators considered… 
Highly Cited
1993
Highly Cited
1993
Analysis of the epitopes of proliferating cell nuclear antigen recognized by monoclonal antibodies.
BACKGROUND Monoclonal antibodies to proliferating cell nuclear antigen (PCNA) are increasingly used for evaluation of cell… 
Highly Cited
1992
Highly Cited
1992
Detection of proliferating cell nuclear antigen in diagnostic histopathology.
We describe the effects of tissue preservation, fixation time, and hydrolytic treatment on the detection of proliferating cell… 
Highly Cited
1990
Highly Cited
1990
Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products
A cDNA clone encoding full-length human proliferating cell nuclear antigen (PCNA) was used to generate a panel of in vitro… 
Highly Cited
1983
Highly Cited
1983
Indirect immunofluorescence studies of proliferating cell nuclear antigen in nucleoli of human tumor and normal tissues.
A proliferating cell nuclear antigen (PCNA) was identified with autoantibodies from a patient with systemic lupus erythematosus… 
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