Proliferating Cell Nuclear Antigen

Known as: Proliferating Cell Nuclear Antigen [Chemical/Ingredient], Cyclin, PCNA 
Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading… (More)
National Institutes of Health

Related topics

Related topics

28 relations
Cell CycleCell Cycle ControlDNA RepairDNA Replication
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Broader (3)

Cell Cycle ProteinsCyclinsNuclear Proteins

Narrower (8)

Cyclin ACyclin BCyclin B1PCNA1 antigen, Arabidopsis
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Papers overview

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Highly Cited
2008
Highly Cited
2008
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells.
After exposure to DNA-damaging agents that block the progress of the replication fork, monoubiquitination of proliferating cell… (More)
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Highly Cited
1997
Highly Cited
1997
PCF1 and PCF2 specifically bind to cis elements in the rice proliferating cell nuclear antigen gene.
We have previously defined the promoter elements, sites IIa and IIb, in the rice proliferating cell nuclear antigen (PCNA) gene… (More)
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Highly Cited
1994
Highly Cited
1994
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.
GADD45 is a ubiquitously expressed mammalian gene that is induced by DNA damage and certain other stresses. Like another p53… (More)
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Highly Cited
1992
Highly Cited
1992
Proliferating cell nuclear antigen is required for DNA excision repair.
Fractionation of extracts from human cell lines allows nucleotide excision repair of damaged DNA to be resolved into discrete… (More)
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Highly Cited
1990
Highly Cited
1990
Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: an index of cell proliferation with evidence of deregulated expression in some neoplasms.
Proliferating cell nuclear antigen (PCNA) is a 36 kD nuclear protein associated with the cell cycle. A monoclonal antibody, PC10… (More)
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Highly Cited
1990
Highly Cited
1990
Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form.
The proliferating cell nuclear antigen, PCNA, has recently been identified as the polymerase delta accessory protein. PCNA is… (More)
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Highly Cited
1989
Highly Cited
1989
Regulation of proliferating cell nuclear antigen during the cell cycle.
The proliferating cell nuclear antigen (PCNA), also known as cyclin and DNA polymerase delta auxiliary factor, is present in… (More)
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Highly Cited
1987
Highly Cited
1987
Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein
The mechanism of replication of the simian virus 40 (SV40) genome closely resembles that of cellular chromosomes, thereby… (More)
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Highly Cited
1987
Highly Cited
1987
Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites
Pulse-chase experiments have revealed that cyclin, the auxiliary protein of DNA polymerase-delta, is stable during the transition… (More)
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Highly Cited
1984
Highly Cited
1984
Identity of the proliferating cell nuclear antigen and cyclin
Studies of growth regulation and cellular transformation will be assisted by the identification of proteins that are… (More)
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