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Proliferating Cell Nuclear Antigen
Known as:
Proliferating Cell Nuclear Antigen [Chemical/Ingredient]
, Cyclin
, PCNA
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Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading…
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National Institutes of Health
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Related topics
Related topics
29 relations
Cell Cycle
Cell Cycle Control
DNA Repair
DNA Replication
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Broader (3)
Cell Cycle Proteins
Cyclins
Nuclear Proteins
Narrower (9)
Cyclin A
Cyclin B
Cyclin B1
PCNA1 antigen, Arabidopsis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Replication Factor C Disengages from Proliferating Cell Nuclear Antigen (PCNA) upon Sliding Clamp Formation, and PCNA Itself Tethers DNA Polymerase δ to DNA*
V. Podust
,
N. Tiwari
,
Scott J Stephan
,
E. Fanning
Journal of Biological Chemistry
1998
Corpus ID: 20447300
Replication factor C (RF-C) and proliferating cell nuclear antigen (PCNA) assemble a complex, called sliding clamp, onto DNA. The…
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Highly Cited
1997
Highly Cited
1997
The prepubertal testis (prenatal and postnatal): its relationship to intratubular germ cell neoplasia: a combined Pediatric Oncology Group and Children's Cancer Study Group.
E. Hawkins
,
S. Heifetz
,
R. Giller
,
B. Cushing
Human Pathology
1997
Corpus ID: 12002964
Highly Cited
1995
Highly Cited
1995
Proliferation of renal cell carcinoma assessed by fixation‐resistant polyclonal Ki‐67 antibody labeling. Correlation with clinical outcome
B. Delahunt
,
P. Bethwaite
,
A. Thornton
,
J. Ribas
Cancer
1995
Corpus ID: 21467528
Background. Although tumor staging is an important prognostic parameter for renal cell carcinoma (RCC), postnephrectomy survival…
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1995
1995
Proliferating cell nuclear antigen (PCNA) expression in oral squamous cell carcinomas.
S. Tsai
,
Y. Jin
Journal of Oral Pathology & Medicine
1995
Corpus ID: 3259545
Proliferating cell nuclear antigen (PCNA) is a nuclear protein synthesized in the late G1 and S phase of the cell cycle which can…
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Highly Cited
1994
Highly Cited
1994
Evidence for a protein domain superfamily shared by the cyclins, TFIIB and RB/p107.
Toby J. Gibson
,
Julie D. Thompson
,
Ariel Blocker
,
Tony Kouzarides
Nucleic Acids Research
1994
Corpus ID: 327012
Cyclins, TFIIB and RB play major roles in cell cycle and/or gene regulation. Earlier work has suggested common ancestry for the…
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Highly Cited
1993
Highly Cited
1993
Analysis of the epitopes of proliferating cell nuclear antigen recognized by monoclonal antibodies.
G. Roos
,
G. Landberg
,
J. Huff
,
R. Houghten
,
Y. Takasaki
,
E. Tan
Laboratory investigation; a journal of technical…
1993
Corpus ID: 45368209
BACKGROUND Monoclonal antibodies to proliferating cell nuclear antigen (PCNA) are increasingly used for evaluation of cell…
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Highly Cited
1992
Highly Cited
1992
Detection of proliferating cell nuclear antigen in diagnostic histopathology.
H. Wolf
,
K. Dittrich
Journal of Histochemistry and Cytochemistry
1992
Corpus ID: 29134039
We describe the effects of tissue preservation, fixation time, and hydrolytic treatment on the detection of proliferating cell…
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Highly Cited
1990
Highly Cited
1990
Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products
J. Huff
,
G. Roos
,
+4 authors
W. Keck
Journal of Experimental Medicine
1990
Corpus ID: 5748677
A cDNA clone encoding full-length human proliferating cell nuclear antigen (PCNA) was used to generate a panel of in vitro…
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Highly Cited
1987
Highly Cited
1987
Epitopes on proliferating cell nuclear antigen recognized by human lupus autoantibody and murine monoclonal antibody.
K. Ogata
,
Y. Ogata
,
Y. Takasaki
,
E. Tan
Journal of Immunology
1987
Corpus ID: 25255054
The immune epitopes of proliferating cell nuclear antigen (PCNA), also called cyclin, were analyzed by determining the reactivity…
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Highly Cited
1983
Highly Cited
1983
Indirect immunofluorescence studies of proliferating cell nuclear antigen in nucleoli of human tumor and normal tissues.
P. K. Chan
,
R. Frakes
,
E. Tan
,
M. Brattain
,
K. Smetana
,
H. Busch
Cancer Research
1983
Corpus ID: 15610688
A proliferating cell nuclear antigen (PCNA) was identified with autoantibodies from a patient with systemic lupus erythematosus…
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