Skip to search formSkip to main contentSkip to account menu

Proliferating Cell Nuclear Antigen

Known as: Proliferating Cell Nuclear Antigen [Chemical/Ingredient], Cyclin, PCNA 
Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading… 
National Institutes of Health

Related topics

Related topics

29 relations
Cell CycleCell Cycle ControlDNA RepairDNA Replication

Broader (3)

Cell Cycle ProteinsCyclinsNuclear Proteins

Narrower (9)

Cyclin ACyclin BCyclin B1PCNA1 antigen, Arabidopsis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Proliferating Cell Nuclear Antigen Is a Novel Inhibitory Ligand for the Natural Cytotoxicity Receptor NKp44
NK cells play an important role in the early immune response to cancer. The NKp44 activating receptor is the only natural… 
Highly Cited
2006
Highly Cited
2006
Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination
Differential modifications of proliferating cell nuclear antigen (PCNA) determine DNA repair pathways at stalled replication… 
Highly Cited
2004
Highly Cited
2004
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
A single double-strand break (DSB) induced by HO endonuclease triggers both repair by homologous recombination and activation of… 
Highly Cited
2001
Highly Cited
2001
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
The Ddc1/Rad17/Mec3 complex and Rad24 are DNA damage checkpoint components with limited homology to replication factors PCNA and… 
Highly Cited
1998
Highly Cited
1998
Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1.
Activation of the Cyclin B/Cdc2 kinase complex triggers entry into mitosis in all eukaryotic cells. Cyclin B1 localization… 
Highly Cited
1995
Highly Cited
1995
Antigen retrieval immunohistochemistry under the influence of pH using monoclonal antibodies.
Antigen retrieval (AR) incorporating high-temperature microwave (MW) heating of tissue sections before immunostaining is a… 
Highly Cited
1994
Highly Cited
1994
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
Cdk-interacting protein 1 (Cip1) is a p53-regulated 21-kDa protein that inhibits several members of the cyclin-dependent kinase… 
Highly Cited
1994
Highly Cited
1994
Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.
DNA damage frequently leads to the production of apurinic/apyrimidinic (AP) sites, which are presumed to be repaired through the… 
Highly Cited
1991
Highly Cited
1991
Prognostic value of proliferating cell nuclear antigen in gastric carcinoma.
A new monoclonal antibody to proliferating cell nuclear antigen (PCNA), PC10, which can be used on routinely processed tissue… 
Highly Cited
1988
Highly Cited
1988
Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis
UV irradiation of quiescent human fibroblasts immediately triggers the appearance of the nuclear protein cyclin/proliferating… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)