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Here we show that the functional human ortholog of Greatwall protein kinase (Gwl) is the microtubule-associated serine/threonine… Expand In the Drosophila embryo, Nanos and Pumilio collaborate to repress the translation of hunchback mRNA in the somatic cytoplasm… Expand In the presence of unattached/weakly attached kinetochores, the spindle assembly checkpoint (SAC) delays exit from mitosis by… Expand Cyclin B is degraded at the onset of anaphase by a ubiquitin-dependent proteolytic system. We have fractionated mitotic Xenopus… Expand Human immunodeficiency virus type 1 (HIV-1) vpr inhibits the replication of tumor cell lines and peripheral blood mononuclear… Expand In eukaryotic cells, the onset of mitosis involves cyclin molecules which interact with proteins of the cdc2 family to produce… Expand We have used immunofluorescence staining to study the subcellular distribution of cyclin A and B1 during the somatic cell cycle… Expand A cyclin B homolog was identified in Saccharomyces cerevisiae using degenerate oligonucleotides and the polymerase chain reaction… Expand CYCLINS are proteins synthesized during each cell cycle and abruptly destroyed in each mitosis1–5. Cyclins have been implicated… Expand We have cloned, sequenced, and characterized the expression of a Drosophila cyclin B gene. The independent evolutionary… Expand