Cyclins

Known as: Cyclin, Cyclins [Chemical/Ingredient] 
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non… (More)
  • figure 1
Is this relevant?
Review
2017
Review
2017
Cancer is characterized by uncontrolled tumour cell proliferation resulting from aberrant activity of various cell cycle proteins… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 1
Is this relevant?
Review
2016
Review
2016
Mammalian cells encode three D cyclins (D1, D2, and D3) that coordinately function as allosteric regulators of cyclin-dependent… (More)
  • figure 1
  • figure 2
  • table 1
Is this relevant?
Review
2011
Review
2011
Cyclin D1, and to a lesser extent the other D-type cyclins, is frequently deregulated in cancer and is a biomarker of cancer… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Review
2005
Review
2005
Cyclin-dependent kinases (Cdks) are the catalytic subunits of a family of mammalian heterodimeric serine/threonine kinases that… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure I
Is this relevant?
Review
2004
Review
2004
I discuss advances in the cell cycle in the 21 years since cyclin was discovered. The surprising redundancy amongst the classical… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2004
Review
2004
Entry into, progression through, and exit from the G1 phase of the mammalian cell cycle in response to extracellular mitogenic… (More)
  • figure 1
  • table 1
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Breast cancer is the most common malignancy among women. Most of these cancers overexpress cyclin D1, a component of the core… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
1995
Review
1995
D-type cyclins couple extracellular signals to the biochemical machinery that governs progression through G1 phase of the… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
THE division cycle of eukaryotic cells is regulated by a family of protein kinases known as the cyclin-dependent kinases (CDKs)1… (More)
Is this relevant?