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Cyclins

Known as: Cyclin, Cyclins [Chemical/Ingredient] 
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The cyclin-dependent kinase (CDK)–RB–E2F axis forms the core transcriptional machinery driving cell cycle progression, dictating… Expand
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Review
2018
Review
2018
Since their characterization as conserved modules that regulate progression through the eukaryotic cell cycle, cyclin-dependent… Expand
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Review
2004
Review
2004
Entry into, progression through, and exit from the G1 phase of the mammalian cell cycle in response to extracellular mitogenic… Expand
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Review
2004
Review
2004
I discuss advances in the cell cycle in the 21 years since cyclin was discovered. The surprising redundancy amongst the classical… Expand
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Highly Cited
1998
Highly Cited
1998
The activities of cyclin D-dependent kinases serve to integrate extracellular signaling during G1 phase with the cell-cycle… Expand
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Review
1995
Review
1995
  • C. Sherr
  • Trends in biochemical sciences
  • 1995
  • Corpus ID: 43243291
D-type cyclins couple extracellular signals to the biochemical machinery that governs progression through G1 phase of the… Expand
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Highly Cited
1993
Highly Cited
1993
The cyclin-dependent kinase Cdk2 associates with cyclins A, D, and E and has been implicated in the control of the G1 to S phase… Expand
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Highly Cited
1993
Highly Cited
1993
DEREGULATION of cell proliferation is a hallmark of neoplastic transformation. Alteration in growth control pathways must… Expand
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Highly Cited
1993
Highly Cited
1993
THE division cycle of eukaryotic cells is regulated by a family of protein kinases known as the cyclin-dependent kinases (CDKs)1… Expand
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Highly Cited
1991
Highly Cited
1991
Cyclin degradation is the key step governing exit from mitosis and progress into the next cell cycle. When a region in the N… Expand
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