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Cyclins

Known as: Cyclin, Cyclins [Chemical/Ingredient] 
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME… 
National Institutes of Health

Related topics

Related topics

38 relations

Narrower (15)

CCNE2 protein, humanCLN1 protein, Candida albicansCables1 protein, mouseCcnl1 protein, rat
CCNJ geneCNNM1 geneCNNM2 geneCNNM3 gene

Broader (1)

Cell Cycle Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Growth Inhibition and G1 Cell Cycle Arrest Mediated by 25-Methoxyhispidol A, a Novel Triterpenoid, Isolated from the Fruit of Poncirus trifoliata in Human Hepatocellular Carcinoma Cells
Poncirus trifoliata P. trifoliata P. trifoliata P. trifoliata 
Review
2007
Review
2007
Systematic review: the application of molecular pathogenesis to prevention and treatment of oesophageal adenocarcinoma
Oesophageal adenocarcinoma is an increasingly common cancer with a poor prognosis. It develops in a stepwise progression from… 
2007
2007
The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses proliferation and invasion of human oral squamous carcinoma cells via p53 independent and MMP, uPAR dependent…
  • 김진
  • 2007
  • Corpus ID: 116566917
2000
2000
Higher levels of cell proliferation rate and cyclin CycD3 expression in the Arabidopsis amp1 mutant.
Cytokinins are involved in plant cell proliferation leading to plant growth and morphogenesis. The amp1 mutant of Arabidopsis has… 
1999
1999
p 53 regulates a G 2 checkpoint through cyclin B 1 ( cell cycle y cdc 2 y mitosis y cancer )
The p53 tumor suppressor controls multiple cell cycle checkpoints regulating the mammalian response to DNA damage. To identify… 
1999
1999
The shuffling of a mortal coil
4 nature genetics • volume 22 • may 1999 Perhaps the most important, and unappreciated, outcome of both the Industrial and… 
1998
1998
Immunohistochemical study of cyclins D and E and cyclin dependent kinase (cdk) 2 and 4 in human endometrial carcinoma.
We studied the immunolocalization of cyclins D1 and E and their corresponding partner cyclin dependent kinases (cdk), cdk4 and… 
1998
1998
Structure-based inhibitor design for CDK2, a cell cycle controlling protein kinase
Abstract 
Highly Cited
1997
Highly Cited
1997
Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4
We demonstrate in this paper that the G1 phase specific cell cycle regulator cyclin E is able to provoke focus formation when… 
Highly Cited
1997
Highly Cited
1997
Down-regulation of the Cyclin A Promoter by Transforming Growth Factor-β1 Is Associated with a Reduction in Phosphorylated Activating Transcription Factor-1 and Cyclic AMP-responsive Element-binding…
Transforming growth factor (TGF)-β1 prevents cell cycle progression by inhibiting several regulators, including cyclin A. To… 
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