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CCNE2 protein, human

Known as: Cyclin E2, Cyclin-E2, CCNE2 
G1/S-specific cyclin-E2 (404 aa, ~47 kDa) is encoded by the human CCNE2 gene. This protein plays a role in cell cycle checkpoint regulation between… 
National Institutes of Health

Related topics

Related topics

9 relations
CCNE2 geneCell Cycle ControlCell NucleusGenes, Regulator

Broader (1)

Cyclins

Papers overview

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Highly Cited
2017
Highly Cited
2017
Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells.
Molecular networks governing responses to targeted therapies in cancer cells are complex dynamic systems that demonstrate… 
Highly Cited
2017
Highly Cited
2017
Knockdown of Long Non-Coding RNA KCNQ1OT1 Restrained Glioma Cells’ Malignancy by Activating miR-370/CCNE2 Axis
Accumulating evidence has highlighted the potential role of long non-coding RNAs (lncRNAs) as biomarkers and therapeutic targets… 
2016
2016
Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of…
Gene expression profiling has been suggested to predict breast cancer outcome. The prognostic value of the 8q22-24 position in… 
Highly Cited
2015
Highly Cited
2015
MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer.
Highly Cited
2015
Highly Cited
2015
Tumour-suppressive microRNA-144-5p directly targets CCNE1/2 as potential prognostic markers in bladder cancer
Background:Analysis of a microRNA (miRNA) expression signature of bladder cancer (BC) by deep-sequencing revealed that clustered… 
Highly Cited
2012
Highly Cited
2012
Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells
Objective Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients… 
Highly Cited
2012
Highly Cited
2012
NEUROG2 Drives Cell Cycle Exit of Neuronal Precursors by Specifically Repressing a Subset of Cyclins Acting at the G1 and S Phases of the Cell Cycle
ABSTRACT Proneural NEUROG2 (neurogenin 2 [Ngn2]) is essential for neuronal commitment, cell cycle withdrawal, and neuronal… 
Highly Cited
2009
Highly Cited
2009
The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene
CHD8 is a chromatin remodeling ATPase of the SNF2 family. We found that depletion of CHD8 impairs cell proliferation. In order to… 
Highly Cited
2009
Highly Cited
2009
Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin.
BACKGROUND & AIMS E-cyclins control the transition of quiescent cells into the cell cycle. Two E-cyclins, CcnE1 and CcnE2, have… 
2009
2009
Evidence that human blastomere cleavage is under unique cell cycle control
PurposeTo understand the molecular pathways that control early human embryo development.MethodsImproved methods of linear… 
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