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Fibrillarin: a new protein of the nucleolus identified by autoimmune sera
Fibrillarin is a widely occurring basic nonhistone nucleolar protein whose location and nuclease sensitivity may indicate some structural and/or functional role in the rDNA‐containing dense fibrillar and fibrillsar center regions of the nucleolus. Expand
Cloning and Characterization of GEF-H1, a Microtubule-associated Guanine Nucleotide Exchange Factor for Rac and Rho GTPases*
Results suggest that GEF-H1 may have a direct role in activation of Rac and/or Rho and in bringing the activated GTPase to specific target sites such as microtubules. Expand
C23 interacts with B23, a putative nucleolar-localization-signal-binding protein.
Results suggest that the interaction of C23 and B23 may represent a nucleolar-targeting mechanism in which B23 acts as aucleolar-localization signal-binding protein. Expand
Monoclonal autoantibody from a (New Zealand black x New Zealand white)F1 mouse and some human scleroderma sera target an Mr 34,000 nucleolar protein of the U3 RNP particle.
The staining pattern produced by antibody 72B9 in different cell substrates was identical with those obtained by scleroderma antibodies reactive with a basic nucleolar protein of Mr 34,000, which is associated with the U3 RNP particle. Expand
Small Nuclear RNAs: RNA Sequences, Structure, and Modifications
All eukaryotic cells contain multiple small nuclear RNAs, designated U-sn At present ten U-snRNAs have been identified; they account for about 1% total mammalian cellular RNA. Of these, the U1 to U8Expand
The 58-kDa microspherule protein (MSP58), a nucleolar protein, interacts with nucleolar protein p120.
In insect Sf9 cells, recombinant p120 and MSP58 proteins associated with each other, confirming the results of the yeast two-hybrid assay, and Immunofluorescence indicated that the MSP 58 protein is localized in microspherules in the nucleolus. Expand
Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24.
  • I. Goldknopf, H. Busch
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 March 1977
It is indicated that protein A24 has two amino termini and one carboxyl terminus, and the branched structure ofprotein A24 proposed is: (see text). Expand
Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth.
A cDNA encoding human nucleophosmin (protein B23) was obtained by screening a human placental cDNA library in lambda gtll first with monoclonal antibody to rat nucleophosmin and then with confirmedExpand
Nucleologenesis: Composition and fate of prenucleolar bodies
Results demonstrate that the nucleolus is formed by fusion of prenucleolar structures whose biochemical composition resembles the matureucleolus, since PNBs contain at least two of the major nucleolar proteins. Expand
Translocation of nucleolar phosphoprotein B23 (37 kDa/pI 5.1) induced by selective inhibitors of ribosome synthesis.
To elucidate the possible role of nucleolar phosphoprotein B23 in ribosome synthesis, drugs which inhibit the processing of ribosomal RNA were employed and protein B23 was found co-localized with the pre-rRNPs as determined by ELISA assays which agrees with previous studies. Expand