Cyclin B1

Known as: G2/Mitotic-Specific Cyclin-B1, CCNB1, Cyclin-B1 
G2/mitotic-specific cyclin-B1 (433 aa, ~48 kDa) is encoded by the human CCNB1 gene. This protein plays a role in mediating the progression of the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Cyclin B1–Cdk1 is the key initiator of mitosis, but when and where activation occurs has not been precisely determined in… (More)
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Review
2003
Review
2003
Formation of an active nuclear cyclin B1-CDK1 complex is a highly intricate procedure requiring many different levels of… (More)
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Highly Cited
2001
Highly Cited
2001
In vertebrate cells, the nuclear entry of Cdc2–cyclin B1 (MPF) during prophase is thought to be essential for the induction and… (More)
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Highly Cited
2001
Highly Cited
2001
The initiation of mitosis requires the activation of M-phase promoting factor (MPF). MPF activation and its subcellular… (More)
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Highly Cited
1999
Highly Cited
1999
The proteolysis of key regulatory proteins is thought to control progress through mitosis. Here we analyse cyclin B1 degradation… (More)
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Highly Cited
1999
Highly Cited
1999
The p53 tumor suppressor controls multiple cell cycle checkpoints regulating the mammalian response to DNA damage. To identify… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND At M phase, cyclin B1 is phosphorylated in the cytoplasmic retention sequence (CRS), which is required for nuclear… (More)
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Highly Cited
1998
Highly Cited
1998
Mitosis in human cells is initiated by the protein kinase Cdc2-cyclin B1, which is activated at the end of G2 by… (More)
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Highly Cited
1998
Highly Cited
1998
M-phase-promoting factor (MPF), a complex of cdc2 and a B-type cyclin, is a key regulator of the G2/M cell cycle transition… (More)
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Highly Cited
1997
Highly Cited
1997
We have shown previously that M-phase phospho-epitopes accumulate in neuronal tau proteins incorporated into the hallmark… (More)
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