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I discuss advances in the cell cycle in the 21 years since cyclin was discovered. The surprising redundancy amongst the classical… Expand Abstract. The cell cycle is controlled by numerous mechanisms ensuring correct cell division. This review will focus on these… Expand The genome-wide program of gene expression during the cell division cycle in a human cancer cell line (HeLa) was characterized… Expand Beneath the complexity and idiopathy of every cancer lies a limited number of 'mission critical' events that have propelled the… Expand The events of the cell cycle of most organisms are ordered into dependent pathways in which the initiation of late events is… Expand We have produced extracts of frog eggs that can perform multiple cell cycles in vitro. Destruction of the endogenous messenger… Expand The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present… Expand Mechanical chopping of plant tissues in the presence of mithramycin released intact nuclei representative of the cells within the… Expand A rapid method for the flow microfluorometric determination of the DNA content per cell is described. Incubation of cells in a… Expand Mitotic cell division in eukaryotes is accomplished through a highly reproducible temporal sequence of events that is common to… Expand