Cyclin A

Known as: Adenovirus E1A Associated Protein p60, Type A Cyclin, Type A Cyclins 
A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It plays a role in progression of the CELL CYCLE through… (More)
National Institutes of Health

Papers overview

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Review
2002
Review
2002
Cyclin A is particularly interesting among the cyclin family because it can activate two different cyclin-dependent kinases (CDKs… (More)
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Highly Cited
2002
Highly Cited
2002
Pluripotent cells of embryonic origin proliferate at unusually rapid rates and have a characteristic cell cycle structure with… (More)
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Highly Cited
2001
Highly Cited
2001
Mitosis is controlled by the specific and timely degradation of key regulatory proteins, notably the mitotic cyclins that bind… (More)
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Highly Cited
2001
Highly Cited
2001
Cyclin A is a stable protein in S and G2 phases, but is destabilized when cells enter mitosis and is almost completely degraded… (More)
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Highly Cited
1998
Highly Cited
1998
An important question in the cell cycle field is how cyclin-dependent kinases (cdks) target their substrates. We have studied the… (More)
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Highly Cited
1996
Highly Cited
1996
The crystal structure of the human p27Kip1 kinase inhibitory domain bound to the phosphorylated cyclin A–cyclin-dependent kinase… (More)
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Highly Cited
1994
Highly Cited
1994
gamma-Irradiation of human diploid fibroblasts in the G1 interval caused arrest of the cell cycle prior to S phase. This cell… (More)
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Highly Cited
1993
Highly Cited
1993
The cyclin-dependent kinase Cdk2 associates with cyclins A, D, and E and has been implicated in the control of the G1 to S phase… (More)
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Highly Cited
1992
Highly Cited
1992
Cyclins play a fundamental role in regulating cell cycle events in all eukaryotic cells. The human cyclin A gene was identified… (More)
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Highly Cited
1991
Highly Cited
1991
Cyclin A protein is synthesized and localized into the nucleus at the onset of S phase in nontransformed mammalian fibroblasts… (More)
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