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Primaquine

Known as: 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline, Primaquin, Primachin 
A synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the… 
National Institutes of Health

Related topics

Related topics

26 relations

Narrower (11)

2-tert-butylprimaquine5-hydroxyprimaquine6-demethylprimaquineM 8506

Broader (2)

AntimalarialsQuinolines
Decreased Protein Synthesis [PE]Drug AllergyIn BloodMalaria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Improving the radical cure of vivax malaria (IMPROV): a study protocol for a multicentre randomised, placebo-controlled comparison of short and long course primaquine regimens
BackgroundPlasmodium vivax malaria is a major cause of morbidity and recognised as an important contributor to mortality in some… 
Review
2014
Review
2014
The clinical and public health problem of relapse despite primaquine therapy: case review of repeated relapses of Plasmodium vivax acquired in Papua New Guinea
BackgroundPrimaquine is the only drug available for preventing relapse following a primary attack by Plasmodium vivax malaria… 
Review
1990
Review
1990
Inhibition of oral contraceptive steroid-metabolizing enzymes by steroids and drugs.
Highly Cited
1987
Highly Cited
1987
Biologically-significant scavenging of the myeloperoxidase-derived oxidant hypochlorous acid by some anti-inflammatory drugs.
Highly Cited
1987
Highly Cited
1987
Inhibition by nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl…
Highly Cited
1986
Highly Cited
1986
Liposomes as drug carriers in leishmaniasis and malaria.
Highly Cited
1977
Highly Cited
1977
Comparison of the Curative Antimalarial Activities and Toxicities of Primaquine and Its d and l Isomers
This investigation was undertaken to determine whether either d-primaquine or l-primaquine has sufficient advantage over… 
1965
1965
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. II. Triazine resistance.
Highly Cited
1962
Highly Cited
1962
Hemoglobin Zurich. I. A new hemoglobin anomaly associated with acute hemolytic episodes with inclusion bodies after sulfonamide therapy.
A new abnormal hemoglobin was observed in 15 members over four generations of a large Swiss family and has been termed… 
Highly Cited
1962
Highly Cited
1962
Hemolytic effect of therapeutic drugs. Clinical considerations of the primaquine-type hemolysis.
FOR MANY YEARS hemolytic reactions have been recognized as hazards which accompany the administration of certain classes of… 
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