Primaquine

Known as: 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline, Primaquin, Primachin 
A synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the… (More)

Topic mentions per year

Topic mentions per year

1949-2018
05010019492017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Falciparum malaria is transmitted by anopheline mosquitoes that have fed on blood containing gametocytes of Plasmodium falciparum… (More)
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2011
2011
Millions of people receive primaquine against sexual plasmodia responsible for malaria transmission. These gametocytes cause no… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Artemisinin-combination therapy (ACT) is recommended as first-line treatment of falciparum malaria throughout the… (More)
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Highly Cited
2008
Highly Cited
2008
Antiviral or antitumor immunity requires activation of cytotoxic CD8+ T cells by dendritic cells, which present viral or tumor… (More)
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2008
2008
Plasmodium vivax causes debilitating but usually non-lethal malaria in most of Asia and South America. Prevention of relapse… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND About a fifth of malaria cases in 1999 for the Kapit division of Malaysian Borneo had routinely been identified by… (More)
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Highly Cited
2004
Highly Cited
2004
The activities of primaquine in combination with quinine or artesunate against asexual- and sexual-stage parasites were assessed… (More)
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2003
2003
The incidence and range of endemic malaria caused by Plasmodium vivax has expanded during the past 30 years. This parasite forms… (More)
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2003
2003
An expanding risk and range of endemic malaria threatens travelers. Primaquine is an old drug recently demonstrated to offer… (More)
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1994
1994
The blood stage antimalarial efficacy of primaquine (0.25 mg of base/kg of body weight/day over 14 days) and chloroquine (25 mg… (More)
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