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Primaquine

Known as: 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline, Primaquin, Primachin 
A synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Glucose-6-phosphate dehydrogenase (G6PD) is a potentially pathogenic inherited enzyme abnormality and, similar to other human red… Expand
Review
2011
Review
2011
Primaquine was officially licensed as an anti-malarial drug by the FDA in 1952. It has remained the only FDA licensed drug… Expand
Highly Cited
2010
Highly Cited
2010
Summary Background Artemisinin-combination therapy (ACT) is recommended as first-line treatment of falciparum malaria throughout… Expand
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Review
2009
Review
2009
Primaquine was firstly synthesized in 1946 in the USA, and is the most representative member of the anti-malarial 8… Expand
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Highly Cited
2008
Highly Cited
2008
Primaquine (PQ) is one of the most widely used antimalarial and is the only available drug till date to combat relapsing form of… Expand
Review
2004
Review
2004
Primaquine is the only available drug for preventing relapse of malaria, and confusion surrounds its use. This review examines… Expand
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Highly Cited
2001
Highly Cited
2001
We tested tafenoquine (WR 238605), a new long-acting 8-aminoquinoline, for its ability to prevent malaria in an area that is… Expand
Highly Cited
1999
Highly Cited
1999
Depletion of Ca2+ stores in Xenopus oocytes activated entry of Ca2+ across the plasma membrane, which was measured as a current I… Expand
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Review
1959
Review
1959
It has been recognized for a long time that 8-aminoquinoline compounds may cause hemolytic anemia in certain individuals, but… Expand
Highly Cited
1956