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The antimalarial activity of some quinolone esters.
Lysosomes, pH and the Anti-malarial Action of Chloroquine
MALARIA parasites1 or mammalian liver2 suitably exposed to chloroquine rapidly form autophagic vacuoles; in the case of the parasites, these are visible under the light microscope because they
The antimalarial activity of N-benzyloxydihydrotriazines. I. The activity of clociguanil (BRL 50216) against rodent malaria, and studies on its mode of action.
A series of N-benzyloxydihydrotriazines were prepared and found to have antimalarial activity against Plasmodium berghei infections in mice. One of the most active of these compounds. 4,6-diamino-1...
Phlebotomus sergenti, a vector of Leishmania tropica in Saudi Arabia.
The Leishmaniases in biology and medicine
The Leishmaniases in biology and medicine is a treatise on the history of leishmaniasis and its role in modern medicine.
The chemotherapy of rodent malaria, XXII. The value of drug-resistant strains of P. berghei in screening for blood schizontocidal activity.
  • W. Peters
  • Biology, Medicine
    Annals of tropical medicine and parasitology
  • 1 June 1975
It is concluded that the in vivo tests do provide a valuable indication of the potential use of a compound against drug-resistant malaria parasites of man and of the future value of new compounds against strains of parasites that are already resistant to chloroquine.
The chemotherapy of rodent malaria, XXIII Causal prophylaxis, part II: Practical experience with Plasmodium yoelii nigeriensis in drug screening.
It is concluded that a rodent malaria-mouse model does provide a relatively simple model for the screening of drugs for causal prophylaxis, and the data so obtained are of relevance to the detection of causalProphylactics against human malaria.
Mechanisms of Artemisinin Resistance in the Rodent Malaria Pathogen Plasmodium yoelii
The phenotype of artemisinin resistance in P. yoelii appears to be multifactorial, particularly within the parasite, where the drug appeared to react with the same parasite proteins in both strains.