Pramlintide

Known as: LYS-CYS-ASN-THR-ALA-THR-CYS-ALA-THR-GLN-ARG-LEU-ALA-ASN-PHE-LEU-VAL-HIS-SER-SER-ASN-ASN-PHE-GLY-PRO-ILE-LEU-PRO-PRO-THR-ASN-VAL-GLY-SER-ASN-THR-TYR-NH2, Triproamylin, pramlintide [Chemical/Ingredient] 
A peptide analogue of human amylin with 3 proline substitutions at positions 25, 28 and 29, with antihyperglycemic activity. By mimicking amylin… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The neurohormonal control of body weight involves a complex interplay between long-term adiposity signals (e.g., leptin), and… (More)
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Highly Cited
2005
Highly Cited
2005
Long-term trials in insulin-treated subjects with type 2 diabetes have shown that adjunctive treatment with the amylin analogue… (More)
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Highly Cited
2004
Highly Cited
2004
AIMS The autoimmune-mediated destruction of pancreatic beta-cells in Type 1 diabetes mellitus renders patients deficient in two… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Several randomized, placebo-controlled, double-blind trials in insulin-treated patients with type 2 diabetes have shown… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Mealtime amylin replacement with the human amylin analog pramlintide, as an adjunct to mealtime insulin replacement… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE To assess the effect of mealtime amylin replacement with pramlintide on long-term glycemic and weight control in… (More)
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Highly Cited
2001
Highly Cited
2001
The human organic anion transporting polypeptide-C (OATP-C) (gene SLC21A6) is a liver-specific transporter importantly involved… (More)
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Review
1996
Review
1996
The features of three distinct protein phosphorylation cascades in mammalian cells are becoming clear. These signalling pathways… (More)
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Highly Cited
1987
Highly Cited
1987
Peptides containing the tripeptide sequence Arg-Gly-Asp can duplicate or inhibit the cell attachment-promoting effects of… (More)
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Highly Cited
1983
Highly Cited
1983
Conformational aspects of N-glycosylation have been investigated with a series of proline-containing peptides as molecular probes… (More)
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