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Pramlintide

Known as: LYS-CYS-ASN-THR-ALA-THR-CYS-ALA-THR-GLN-ARG-LEU-ALA-ASN-PHE-LEU-VAL-HIS-SER-SER-ASN-ASN-PHE-GLY-PRO-ILE-LEU-PRO-PRO-THR-ASN-VAL-GLY-SER-ASN-THR-TYR-NH2, Triproamylin, pramlintide [Chemical/Ingredient] 
A peptide analogue of human amylin with 3 proline substitutions at positions 25, 28 and 29, with antihyperglycemic activity. By mimicking amylin… 
National Institutes of Health

Related topics

Related topics

11 relations
1.5 ML pramlintide acetate 1 MG/ML Pen Injector2.7 ML pramlintide acetate 1 MG/ML Pen Injector [Symlin]Appetite Suppression [PE]Diabetes Mellitus, Insulin-Dependent

Broader (2)

AmylinHypoglycemic Agents

Narrower (2)

Symlinpramlintide acetate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects: a phase 2, randomized, placebo-controlled, dose-escalation study.
CONTEXT In previous 1-yr trials, treatment with pramlintide (120 microg), an analog of the beta-cell hormone amylin, induced… 
Highly Cited
2005
Highly Cited
2005
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.
The Lass (longevity-assurance homologue) family members, which are highly conserved among eukaryotes, function in ceramide… 
Highly Cited
2002
Highly Cited
2002
A randomized study and open-label extension evaluating the long-term efficacy of pramlintide as an adjunct to insulin therapy in type 1 diabetes.
OBJECTIVE To assess the effect of mealtime amylin replacement with pramlintide on long-term glycemic and weight control in… 
Highly Cited
1999
Highly Cited
1999
Evolution of an antifreeze glycoprotein
The ice-binding antifreeze glycoprotein (AFGP) that circulates in the blood of Antarctic notothenioid fishes enables them to… 
Highly Cited
1997
Highly Cited
1997
Natural variation in a Drosophila clock gene and temperature compensation.
The threonine-glycine (Thr-Gly) encoding repeat within the clock gene period of Drosophila melanogaster is polymorphic in length… 
Review
1996
Review
1996
Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling.
The features of three distinct protein phosphorylation cascades in mammalian cells are becoming clear. These signalling pathways… 
Highly Cited
1992
Highly Cited
1992
The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.
Highly Cited
1988
Highly Cited
1988
Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein.
The peptide p89-101 (Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro) of myelin basic protein is encephalitogenic in mice… 
Highly Cited
1976
Highly Cited
1976
Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight
Adipokinetic hormone, isolated from locust corpora cardiaca, has been identified as a blocked pep-tide : PCA–Leu–Asn–Phe–Thr–Pro… 
Highly Cited
1975
Highly Cited
1975
The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.
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