Diabetes Mellitus, Insulin-Dependent
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In the nearly 100 years since the discovery of therapeutic insulin, significant research efforts have been directed at finding… (More)
Several lines of evidence suggest a role for the gut microbiome in type 1 diabetes. Treating diabetes-prone rodents with… (More)
Diabetes is not a single homogeneous disease but composed of many diseases with hyperglycaemia as a common feature. Four factors… (More)
Type 1 diabetes (T1D) is a debilitating autoimmune disease that results from T-cell-mediated destruction of insulin-producing… (More)
Intensive diabetes therapy aimed at achieving near normoglycemia reduces the risk of microvascular and neurologic… (More)
We report that a single-nucleotide polymorphism (SNP) in the gene (PTPN22) encoding the lymphoid protein tyrosine phosphatase… (More)
To evaluate baseline risk factors for coronary artery disease in patients with type 2 diabetes mellitus.
- American journal of human genetics
A population association has consistently been observed between insulin-dependent diabetes mellitus (IDDM) and the "class 1… (More)
Insulin-dependent diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice results from the T-lymphocyte-mediated destruction of… (More)
A polymorphic region flanking the human insulin gene on the short arm of chromosome 11, the insulin-gene-linked DNA polymorphism… (More)