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Immune complexes (IgG and C3) at the motor end-plate in myasthenia gravis: ultrastructural and light microscopic localization and electrophysiologic correlations.
Although there is strong evidence that myasthenia gravis (MG) is caused by an autoimmune reaction to the nicotinic postsynaptic acetylcholine receptor (AChR) protein, immune complexes have never been… Expand
Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes.
BACKGROUND Voltage-gated calcium channels in small-cell lung carcinomas may initiate autoimmunity in the paraneoplastic neuromuscular disorder Lambert-Eaton syndrome. The calcium-channel subtype that… Expand
Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. I. Neurologic, genetic, and electrophysiologic findings in hereditary polyneuropathies.
THIS report gives the neurologic, genetic, and electrophysiologic findings of a prospective study of kinships with different hereditary neurologic disorders having symmetric neurogenic weakness and… Expand
QUANTAL COMPONENTS OF END‐PLATE POTENTIALS IN THE MYASTHENIC SYNDROME *
- E. Lambert, D. Elmqvist
- Chemistry, Medicine
- Annals of the New York Academy of Sciences
- 1 September 1971
About a decade ago Lambert and coworkers26 described the characteristics of neuromuscular transmission in the myasthenic syndrome sometimes associated with bronchogenic carcinoma, and subsequent… Expand
Paucity and disorganization of presynaptic membrane active zones in the lambert‐eaton myasthenic syndrome
Presynaptic membrane active zones are related to synaptic vesicle exocytosis, and the large intramembrane particles in these zones may represent voltage‐sensitive calcium channels. We tested the… Expand
Ulnar nerve conduction velocity and H-reflex in infants and children.
Measurements of conduction velocity of the motor fibers of the ulnar nerve in the segment between the upper part of the arm and the wrist were made in 6 premature infants, 42 full-term newborn infa...
Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. II. Neurologic, genetic, and electrophysiologic findings in various neuronal degenerations.
THE companion paper 1 on this topic considered the inherited hypertrophic neuropathies in which peroneal muscle weakness and atrophy is prominent. In those disorders, a symmetric neurogenic weakness… Expand
Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine recepotr antibodies
- J. Lindstrom, A. Engel, M. Seybold, V. Lennon, E. Lambert
- The Journal of experimental medicine
- 1 September 1976
Passive transfer of experimental autoimmune myasthenia gravis (EAMG) was achieved using the gamma globulin fraction and purified IgG from sera of rats immunized with Electrophus electricus (eel)… Expand
Myasthenic syndrome in patients with amyotrophic lateral sclerosis
DURING THE COURSE of their illness, patients with amyotrophic lateral sclerosis may have complaints of, and may demonstrate on clinical and laboratory examination, unusual puscle fatigability… Expand
Motor and electric activity of the duodenum.
Recordings of pressure and electric potentials from Biebl loops of the duodenum of trained dogs were used to quantitate and to determine relationships among basic electric rhythm (BER), irregular… Expand