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Immune complexes (IgG and C3) at the motor end-plate in myasthenia gravis: ultrastructural and light microscopic localization and electrophysiologic correlations.
- A. Engel, E. Lambert, F. Howard
- Biology, MedicineMayo Clinic proceedings
- 1 May 1977
Findings provide unambiguous evidence for a destructive auto-immune reaction involving the postsynaptic membrance in MG and suggest that immunopharmacologic blockade of AChR and IgG-induced modulation of A ChR may also contribute to the A chR deficiency at the MG end-plates.
Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes.
- V. Lennon, T. Kryzer, E. Lambert
- Medicine, BiologyThe New England journal of medicine
- 1 June 1995
The high frequency of P/Q-type calcium-channel antibodies found in patients with Lambert-Eaton syndrome implies that antibodies of this specificity have a role in the presynaptic pathophysiology of this disorder.
Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. I. Neurologic, genetic, and electrophysiologic findings in hereditary polyneuropathies.
- P. Dyck, E. Lambert
- Medicine, PsychologyArchives of neurology
- 1 June 1968
THIS report gives the neurologic, genetic, and electrophysiologic findings of a prospective study of kinships with different hereditary neurologic disorders having symmetric neurogenic weakness and…
QUANTAL COMPONENTS OF END‐PLATE POTENTIALS IN THE MYASTHENIC SYNDROME *
- E. Lambert, D. Elmqvist
- Medicine, BiologyAnnals of the New York Academy of Sciences
- 1 September 1971
There is no evidence of abnormality of function of the peripheral nerve or muscle fibers themselves that might explain the muscle weakness in the myasthenic syndrome, and the different processes involved in neuromuscular transmission have been presented in detail.
Ulnar nerve conduction velocity and H-reflex in infants and children.
- John E. Thomas, E. Lambert
- MedicineJournal of applied physiology
- 1960
Measurements of conduction velocity of the motor fibers of the ulnar nerve in the segment between the upper part of the arm and the wrist were made in 6 premature infants, 42 full-term newborn infa...
A new myasthenic syndrome with end‐plate acetylcholinesterase deficiency, small nerve terminals, and reduced acetylcholine release
- A. Engel, E. Lambert, M. Gomez
- Biology, MedicineAnnals of neurology
- 1 April 1977
A new myasthenic syndrome is described in a patient whose symptoms began soon after birth and included generalized weakness increased by exertion, easy fatigability, hyporeflexia, and refractoriness…
Paucity and disorganization of presynaptic membrane active zones in the lambert‐eaton myasthenic syndrome
- H. Fukunaga, A. Engel, M. Osame, E. Lambert
- Biology
- 1 November 1982
The findings can explain the reduced quantal release in LEMS, and strongly suggest that active zone particles are targets of the pathogenic autoantibodies recently demonstrated in this disease.
The exercise test in periodic paralysis
- P. McManis, E. Lambert, J. Daube
- MedicineMuscle & nerve
- 1 October 1986
Of 21 patients with clinically definite hypokalemic, hyperkalemic, or normokalemic periodic paralysis, 15 (71%) had a greater than normal increase in compound muscle action potential amplitude during…
Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. II. Neurologic, genetic, and electrophysiologic findings in various neuronal degenerations.
- P. Dyck, E. Lambert
- Medicine, BiologyArchives of neurology
- 1 June 1968
Cases of neuronal degeneration in which peroneal muscle weakness and atrophy is prominent are considered; in this group of cases, conduction velocities of nerves are either normal or slightly low and nerve biopsies show no evidence of segmental demyelinization or hypertrophy of nerve.
Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine recepotr antibodies
- J. Lindstrom, A. Engel, M. Seybold, V. Lennon, E. Lambert
- Biology, MedicineThe Journal of experimental medicine
- 1 September 1976
Passive transfer of experimental autoimmune myasthenia gravis (EAMG) was achieved using the gamma globulin fraction and purified IgG from sera of rats immunized with Electrophus electricus (eel)…
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