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Professional phagocytes have a vast and sophisticated arsenal of microbicidal features. They are capable of ingesting and… Expand The production and deployment of phagocytes are central functions of the hematopoietic system. In the 1950s, radioisotopic… Expand For a long time, superoxide generation by an NADPH oxidase was considered as an oddity only found in professional phagocytes… Expand Mononuclear phagocytes are versatile cells that can express different functional programs in response to microenvironmental… Expand Apoptotic cells are rapidly engulfed by phagocytes to prevent the release of potentially noxious or immunogenic intracellular… Expand Neutrophils and other phagocytes manufacture O(2)(-) (superoxide) by the one-electron reduction of oxygen at the expense of NADPH… Expand HIV-1 vpr encodes a 96-amino acid, nuclear protein whose function is not well understood. Unlike the other lentivirus regulatory… Expand Cells with properties characteristic of mononuclear phagocytes were evaluated for infectivity with five different isolates of the… Expand The products of oxygen reduction (superoxide anion, hydrogen peroxide, hydroxyl radicals) and excitation (singlet oxygen) have… Expand The origin and turnover of efferent populations of mouse mononuclear phagocytes has been described. Mononuclear phagocytes were… Expand