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Neutrophils are the most abundant white blood cells in circulation, and patients with congenital neutrophil deficiencies suffer… Expand TGF-beta blockade significantly slows tumor growth through many mechanisms, including activation of CD8(+) T cells and… Expand BACKGROUND
The scarcity of early biomarkers for acute renal failure has hindered our ability to launch preventive and therapeutic… Expand Neutrophils provide the first line of defense of the innate immune system by phagocytosing, killing, and digesting bacteria and… Expand The first immune cell to arrive at the site of infection is the neutrophil. Upon arrival, neutrophils quickly initiate… Expand IN THE 1880s Elie Metchnikoff observed specialized phagocytic cells ingesting bacteria, and recognized the importance of… Expand WITH increasing frequency, the human neutrophil is being implicated as a mediator of tissue-destructive events in inflammatory… Expand Mechanisms governing the normal resolution processes of inflammation are poorly understood, yet their elucidation may lead to a… Expand We examined the hypothesis that myeloperoxidase (MPO), a plentiful constituent of neutrophils, might serve as a marker for tissue… Expand An in vitro technique is described for assessing the chemotactic activity of soluble substances on motile cells. Antibody-antigen… Expand