IL-17A-producing neutrophil-regulatory Tn lymphocytes

@article{Ley2006IL17AproducingNT,
  title={IL-17A-producing neutrophil-regulatory Tn lymphocytes},
  author={Klaus Ley and Emily Smith and Matthew A. Stark},
  journal={Immunologic Research},
  year={2006},
  volume={34},
  pages={229-242}
}
The proinflammatory cytokine IL-17A, mainly produced by specialized T cells, plays an important homeostatic role in regulating neutrophil production and blood neutrophil counts. This review will assemble and discuss the evidence for this function of IL-17A-producing cells, which are collectively called neutrophil-regulatory T cells or Tn cells. IL-17A-producing lymphocytes are most abundant in the mesenteric lymph node, where they account for 0.15% of all lymphocytes. About 60% of the Tn cells… Expand
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