PSMB8 gene

Known as: PSMB8, beta5i, Proteasome (Prosome, Macropain) Subunit, Beta Type, 8 Gene 
This gene plays a role in both protein catabolism and antigen processing.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
0102019922018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Nakajo-Nishimura syndrome (NNS) is a disorder that segregates in an autosomal recessive fashion. Symptoms include periodic fever… (More)
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2011
2011
Proteasomes are multisubunit proteases that play a critical role in maintaining cellular function through the selective… (More)
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Highly Cited
2010
Highly Cited
2010
We performed homozygosity mapping in two recently reported pedigrees from Portugal and Mexico with an autosomal-recessive… (More)
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Highly Cited
2009
Highly Cited
2009
Carfilzomib is a proteasome inhibitor in clinical development that primarily targets the chymotrypsin-like (CT-L) subunits in… (More)
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Highly Cited
2009
Highly Cited
2009
The immunoproteasome, a distinct class of proteasome found predominantly in monocytes and lymphocytes, is known to shape the… (More)
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Highly Cited
2003
Highly Cited
2003
Huntington's disease (HD) inclusions are stained with anti-ubiquitin and anti-proteasome antibodies. This, together with… (More)
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Highly Cited
2001
Highly Cited
2001
The murine B16 melanoma system represents an important in vivo model for the evaluation of T cell-based immunization and… (More)
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Highly Cited
1998
Highly Cited
1998
LMP2, LMP7, and MECL are interferon gamma-inducible catalytic subunits of vertebrate 20S proteasomes, which can replace… (More)
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Highly Cited
1995
Highly Cited
1995
The 20S proteasome is the enzyme complex responsible for the processing of antigens bound by major histocompatibility complex… (More)
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Highly Cited
1994
Highly Cited
1994
Recent studies have implicated proteasomes in the generation of the antigenic peptides that are presented on major… (More)
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