PCSK9 protein, human

Known as: proprotein convertase subtilisin kexin 9, human, Proprotein Convertase Subtilisin/Kexin Type 9, Neural Apoptosis Regulated Convertase 1 
Proprotein convertase subtilisin/kexin type 9 (692 aa, ~74 kDa) is encoded by the human PCSK9 gene. This protein is involved in the degradation of… (More)
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Medicinal plant-derived bioactive compounds modulate multiple therapeutic targets in cardiovascular diseases (CVDs), rendering… (More)
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Highly Cited
2014
Highly Cited
2014
OBJECTIVES This study sought to evaluate the efficacy and safety of subcutaneous evolocumab compared with oral ezetimibe in… (More)
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Highly Cited
2013
Highly Cited
2013
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a secreted protein that binds to the epidermal growth factor-like-A… (More)
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Highly Cited
2008
Highly Cited
2008
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates low density lipoprotein receptor (LDLR) protein levels and… (More)
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Highly Cited
2008
Highly Cited
2008
Proprotein convertase subtilisin/kexin type 9 (PCSK9) posttranslationally regulates hepatic low-density lipoprotein receptors… (More)
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Highly Cited
2006
Highly Cited
2006
Elevated levels of circulating low-density lipoprotein cholesterol (LDL-C) play a central role in the development of… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Neural apoptosis-regulated convertase (NARC)-1 is the newest member of the proprotein convertase family implicated in… (More)
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Highly Cited
2004
Highly Cited
2004
Proprotein convertase subtilisin kexin 9 (Pcsk9) is a subtilisin serine protease with a putative role in cholesterol metabolism… (More)
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Highly Cited
2004
Highly Cited
2004
The discovery of autosomal dominant hypercholesterolemic patients with mutations in the PCSK9 gene, encoding the proprotein… (More)
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Highly Cited
2003
Highly Cited
2003
Autosomal dominant hypercholesterolemia (ADH; OMIM144400), a risk factor for coronary heart disease, is characterized by an… (More)
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