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PCSK9 protein, human

Known as: proprotein convertase subtilisin kexin 9, human, Proprotein Convertase Subtilisin/Kexin Type 9, Neural Apoptosis Regulated Convertase 1 
Proprotein convertase subtilisin/kexin type 9 (692 aa, ~74 kDa) is encoded by the human PCSK9 gene. This protein is involved in the degradation of… 
National Institutes of Health

Related topics

Related topics

14 relations
Cell surfaceCholesterol HomeostasisEndopeptidasesEndoplasmic Reticulum

Broader (1)

Proprotein Convertase 9

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Prediction of cardiovascular events with levels of proprotein convertase subtilisin/kexin type 9: A systematic review and meta-analysis.
2014
2014
Characterization of a quantitative method to measure free proprotein convertase subtilisin/kexin type 9 in human serum
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that plays an important role in the regulation of… 
2011
2011
Plasma proprotein convertase subtilisin-kexin type 9 does not change during 24h insulin infusion in healthy subjects and type 2 diabetic patients.
2002
2002
Structural Basis of Thermostability
The crystal structures of two thermally stabilized subtilisin BPN′ variants, S63 and S88, are reported here at 1.8 and 1.9… 
1995
1995
Subtilisin Sendai from alkalophilic Bacillus sp.: molecular and enzymatic properties of the enzyme and molecular cloning and characterization of the gene, aprS.
Highly Cited
1993
Highly Cited
1993
Folding of subtilisin BPN': role of the pro-sequence.
Subtilisin BPN' is an extracellular serine protease from Bacillus amyloliquefaciens that requires an N-terminal 77 amino acid pro… 
Highly Cited
1991
Highly Cited
1991
Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution.
Highly Cited
1986
Highly Cited
1986
Biosynthesis of the sialyl-Lex determinant carried by type 2 chain glycosphingolipids (IV3NeuAcIII3FucnLc4, VI3NeuAcV3FucnLc6, and VI3NeuAcIII3V3Fuc2nLc6) in human lung carcinoma PC9 cells.
Highly Cited
1984
Highly Cited
1984
Crystal structure at 2.6 A resolution of the complex of subtilisin BPN' with streptomyces subtilisin inhibitor.
1970
1970
A hydrogen-bond network at the active site of subtilisin BPN'.
Further examination of the active site region in our X-ray crystallographic model of subtilisin BPN' reveals a hydrogen-bond… 
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