Endopeptidases

Known as: Endopeptidase, Peptide Peptidohydrolases, Proteinase 
A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
BACKGROUND & AIMS Hepatitis C virus (HCV) therapy that is highly efficacious, pangenotypic, with a high barrier to resistance and… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Peginterferon-ribavirin therapy is the current standard of care for chronic infection with hepatitis C virus (HCV… (More)
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Highly Cited
2009
Highly Cited
2009
We describe the testing and release of AutoDock4 and the accompanying graphical user interface AutoDockTools. AutoDock4… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND AND METHODS National surveillance data show recent, marked reductions in morbidity and mortality associated with the… (More)
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Review
1997
Review
1997
These results clearly point out that p53 uses a hyThe p53 gene and its protein product have become the drophobic interface in its… (More)
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Highly Cited
1997
Highly Cited
1997
We report here the purification of the third protein factor, Apaf-3, that participates in caspase-3 activation in vitro. Apaf-3… (More)
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Highly Cited
1995
Highly Cited
1995
The protease responsible for the cleavage of poly(ADP-ribose) polymerase and necessary for apoptosis has been purified and… (More)
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Highly Cited
1995
Highly Cited
1995
Treatment of infected patients with ABT-538, an inhibitor of the protease of human immuno-deficiency virus type 1 (HIV-1), causes… (More)
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Highly Cited
1990
Highly Cited
1990
The E6 protein encoded by the oncogenic human papillomavirus types 16 and 18 is one of two viral products expressed in HPV… (More)
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Highly Cited
1988
Highly Cited
1988
One of the obstacles encountered when extracting DNA from a large number of samples is the cumbersome method of deprotein-izing… (More)
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