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Endopeptidases

Known as: Endopeptidase, Peptide Peptidohydrolases, Proteinase 
A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule.
National Institutes of Health

Related topics

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Narrower (37)

ATP-ubiquitin-dependent proteinaseAc1-proteinaseAc2-proteinaseAc3-proteinase
Amylases / CELLULASE / Endopeptidases / LipaseAmylases 180000 UNT / Endopeptidases 114000 UNT / Lipase 36000 UNT Delayed Release Oral CapsuleEnzyme GeneEnzymes

Papers overview

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Highly Cited
1998
Highly Cited
1998
Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.
BACKGROUND Thrombotic thrombocytopenic purpura is a potentially fatal disease characterized by widespread platelet thrombi in the… 
Highly Cited
1998
Highly Cited
1998
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.
Survivin is a member of the inhibitor of apoptosis protein (IAP) family. We investigated the antiapoptotic mechanism of Survivin… 
Highly Cited
1998
Highly Cited
1998
An Induced Proximity Model for Caspase-8 Activation*
The assembly of the CD-95 (Fas/Apo-1) receptor death-inducing signaling complex occurs in a hierarchical manner; the death domain… 
Highly Cited
1996
Highly Cited
1996
The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol
Review
1993
Review
1993
Evolution and taxonomy of positive-strand RNA viruses: implications of comparative analysis of amino acid sequences.
Despite the rapid mutational change that is typical of positive-strand RNA viruses, enzymes mediating the replication and… 
Highly Cited
1989
Highly Cited
1989
Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
We have investigated the effects of ligation of the fibronectin receptor (FnR) on gene expression in rabbit synovial fibroblasts… 
Review
1988
Review
1988
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis.
Cadherins are a family of glycoproteins involved in the Ca2+-dependent cell-cell adhesion mechanism which is detected in most… 
Highly Cited
1988
Highly Cited
1988
Active human immunodeficiency virus protease is required for viral infectivity.
Retroviral proteins are synthesized as polyprotein precursors that undergo proteolytic cleavages to yield the mature viral… 
Highly Cited
1988
Highly Cited
1988
Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
Alzheimer's disease1 is characterized by cerebral deposits of amyloid β-protein (AP) as senile plaque core and vascular amyloid2… 
Highly Cited
1977
Highly Cited
1977
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.
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