Cholesterol Homeostasis

Any of the processes involved in the maintenance of an internal equilibrium of cholesterol within an organism or cell. (Gene Ontology)

Topic mentions per year

Topic mentions per year

1972-2017
05010015019722017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Cholesterol metabolism is tightly regulated at the cellular level. Here we show that miR-33, an intronic microRNA (miRNA) located… (More)
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Highly Cited
2010
Highly Cited
2010
Proper coordination of cholesterol biosynthesis and trafficking is essential to human health. The sterol regulatory element… (More)
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Highly Cited
2004
Highly Cited
2004
Niemann-Pick C1 Like 1 (NPC1L1) is a protein localized in jejunal enterocytes that is critical for intestinal cholesterol… (More)
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Highly Cited
2003
Highly Cited
2003
Autosomal dominant hypercholesterolemia (ADH; OMIM144400), a risk factor for coronary heart disease, is characterized by an… (More)
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Highly Cited
2002
Highly Cited
2002
Using coimmunoprecipitation and tandem mass spectrometry, we identify INSIG-1 as an ER protein that binds the sterol-sensing… (More)
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Highly Cited
2000
Highly Cited
2000
Several nuclear hormone receptors involved in lipid metabolism form obligate heterodimers with retinoid X receptors (RXRs) and… (More)
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Highly Cited
1999
Highly Cited
1999
The turnover of cholesterol in the brain is thought to occur via conversion of excess cholesterol into 24S-hydroxycholesterol, an… (More)
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Highly Cited
1997
Highly Cited
1997
Niemann-Pick type C (NP-C) disease, a fatal neurovisceral disorder, is characterized by lysosomal accumulation of low density… (More)
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Highly Cited
1997
Highly Cited
1997
An integrated human-mouse positional candidate approach was used to identify the gene responsible for the phenotypes observed in… (More)
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Highly Cited
1996
Highly Cited
1996
We have investigated whether side chain-hydroxylated cholesterol species are important for elimination of cholesterol from the… (More)
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