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Receptor-mediated endocytosis: concepts emerging from the LDL receptor system.
PATHWAYS OF RECEPTOR-MEDIATED ENDOCYTOSIS 3 Entry Into Coated Pits 3 Intracellular Routes 4
The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
The nucleotide sequence of a cloned 5.3 kilobase cDNA for the human low density lipoprotein receptor revealed five domains in the 839 amino acid protein: 322 NH2-terminal amino acids, extremely richExpand
The Reelin Receptor ApoER2 Recruits JNK-interacting Proteins-1 and -2*
Correct positioning of neurons during embryonic development of the brain depends, among other processes, on the proper transmission of the reelin signal into the migrating cells via the interplay ofExpand
Chicken oocyte growth is mediated by an eight ligand binding repeat member of the LDL receptor family.
Deposition of the yolk mass components of chicken oocytes, very low density lipoprotein (VLDL) and vitellogenin (VTG), is mediated by a 95 kDa plasma membrane protein, termed VLDL/VTG receptorExpand
The chicken homologue of zona pellucida protein-3 is synthesized by granulosa cells.
Oocyte development within avian ovarian follicles is an intricate process involving yolk deposition and the formation of extraoocytic matrices. Of these, the perivitelline membrane (pvm) not onlyExpand
Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia.
Monoclonal antibodies directed against the low density lipoprotein (LDL) receptor have been prepared by immunization of mice with a partially purified receptor from bovine adrenal cortex. SpleenExpand
The major chicken egg envelope protein ZP1 is different from ZPB and is synthesized in the liver.
The extracellular matrix surrounding vertebrate oocytes is called the zona pellucida in mammals and perivitelline membrane (pvm) in birds. We have analyzed this structure in chicken follicles andExpand
Elements of Neural Adhesion Molecules and a Yeast Vacuolar Protein Sorting Receptor Are Present in a Novel Mammalian Low Density Lipoprotein Receptor Family Member*
Normal cell development depends to a large part on multifunctional proteins that have evolved by recombination of proven modular elements. We now have discovered and characterized in rabbit such aExpand
The PX‐domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor
Sorting nexins (SNXs) comprise a family of proteins characterized by the presence of a phox‐homology domain, which mediates the association of these proteins with phosphoinositides and recruits themExpand
Thrombospondin‐1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration
Apolipoprotein E receptor 2 (ApoER2), very low‐density lipoprotein receptor (VLDLR), and Dab1 are the main components of the Reelin signalling cascade. Reelin is the sole ligand defined so far inExpand
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